Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133627589 . C A CCDS14641.1:NM_000194.2:c.454Cag>Aag_NP_000185.1:p.152Q>K Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 GLN A:151 A:151 127.0 0.706 T -63.4 -21.5 127.0 0.706 0.0 HOH
 3.715
 N
 O
GLN B:151 B:151 120.0 0.667 H -52.5 -40.2 120.0 0.667 0.0 HOH
 2.716
 NE2
 O
GLN C:151 C:151 134.0 0.744 T -58.6 -23.8 134.0 0.744 0.0 HOH
 7.177
 O
 O
GLN D:151 D:151 135.0 0.75 T -63.6 -25.3 135.0 0.75 0.0 HOH
 5.666
 N
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 GLN A:151 A:151 117.0 0.65 H -61.0 -56.5 117.0 0.65 0.0 HOH
 4.677
 O
 O
GLN B:151 B:151 108.0 0.6 T -51.2 -23.8 108.0 0.6 0.0 HOH
 9.365
 OE1
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 GLN A:151 A:151 149.0 0.828 T -66.5 -15.8 149.0 0.828 0.0 HOH
 3.011
 O
 O
GLN B:151 B:151 143.0 0.794 T -71.4 -12.5 143.0 0.794 0.0 HOH
 6.752
 NE2
 O
GLN C:151 C:151 143.0 0.794 T -70.2 -17.9 NA NA NA
GLN D:151 D:151 141.0 0.783 T -61.9 -26.2 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLN A:151 A:151 140.0 0.778 T -68.1 -19.5 140.0 0.778 0.0 HOH
 8.767
 OE1
 O
GLN B:151 B:151 132.0 0.733 T -64.7 -28.4 132.0 0.733 0.0 HOH
 7.164
 N
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLN A:151 A:151 140.0 0.778 H -70.5 -24.9 140.0 0.778 0.0 HOH
 8.312
 O
 O
GLN B:151 B:151 137.0 0.761 T -71.7 -22.2 137.0 0.761 0.0 HOH
 7.167
 OE1
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLN A:151 A:151 145.0 0.806 T -67.6 -17.8 145.0 0.806 0.0 HOH
 8.722
 O
 O
GLN B:151 B:151 135.0 0.75 G -68.4 -24.5 135.0 0.75 0.0 HOH
 7.094
 OE1
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:151 A:151 122.0 0.678 G -63.7 -26.9 122.0 0.678 0.0 HOH
 3.096
 O
 O
GLN B:151 B:151 132.0 0.733 G -75.4 8.5 132.0 0.733 0.0
GLN C:151 C:151 134.0 0.744 T -67.8 -27.7 134.0 0.744 0.0
GLN D:151 D:151 152.0 0.844 G -76.8 -7.1 152.0 0.844 0.0 HOH
 3.796
 CG
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:151 A:151 133.0 0.739 T -59.1 -22.4 133.0 0.739 0.0 HOH
 7.107
 N
 O
GLN B:151 B:151 132.0 0.733 G -80.7 -15.3 132.0 0.733 0.0 HOH
 4.520
 N
 O
GLN C:151 C:151 135.0 0.75 T -69.5 -12.8 135.0 0.75 0.0
GLN D:151 NA:NA DO NA DO DO DO NA NA NA
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:151 A:151 134.0 0.744 T -69.3 -20.4 134.0 0.744 0.0 HOH
 2.701
 OE1
 O
GLN B:151 B:151 118.0 0.656 T -79.1 16.9 118.0 0.656 0.0 HOH
 7.547
 HE21
 O
GLN C:151 C:151 139.0 0.772 G -67.3 -12.7 139.0 0.772 0.0 HOH
 8.250
 HB2
 O
GLN D:151 D:151 152.0 0.844 T -69.1 -8.3 152.0 0.844 0.0 HOH
 2.713
 OE1
 O
GLN E:151 E:151 137.0 0.761 G -75.9 -15.4 NA NA NA
GLN F:151 F:151 145.0 0.806 T -59.4 -36.5 NA NA NA
GLN G:151 G:151 142.0 0.789 H -61.1 -19.5 NA NA NA
GLN H:151 H:151 138.0 0.767 T -69.8 -6.9 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:151 A:151 129.0 0.717 T -61.8 -27.4 129.0 0.717 0.0
GLN B:151 B:151 122.0 0.678 T -79.3 3.1 122.0 0.678 0.0
GLN C:151 C:151 127.0 0.706 T -68.7 -26.6 127.0 0.706 0.0 HOH
 3.331
 NE2
 O
GLN D:151 D:151 136.0 0.756 T -59.3 -35.8 136.0 0.756 0.0
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:151 A:151 138.0 0.767 G -72.0 -15.2 138.0 0.767 0.0 HOH
 2.699
 OE1
 O
GLN B:151 B:151 111.0 0.617 T -74.7 -19.5 111.0 0.617 0.0
GLN C:151 C:151 138.0 0.767 T -69.1 -11.4 138.0 0.767 0.0 HOH
 8.700
 NE2
 O
GLN D:151 D:151 146.0 0.811 G -70.7 -13.6 146.0 0.811 0.0 HOH
 5.938
 OE1
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:151 A:151 141.0 0.783 G -65.0 -23.7 141.0 0.783 0.0
GLN B:151 B:151 138.0 0.767 T -60.6 -23.4 138.0 0.767 0.0 HOH
 8.893
 N
 O
GLN C:151 C:151 123.0 0.683 G -66.1 -32.9 123.0 0.683 0.0 HOH
 8.496
 OE1
 O
GLN D:151 D:151 144.0 0.8 G -96.7 23.3 144.0 0.8 0.0 HOH
 7.539
 CG
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 GLN A:157 A:151 127.0 0.706 T -64.0 -19.0 127.0 0.706 0.0 HOH
 3.787
 CG
 O
GLN B:157 B:151 145.0 0.806 T -63.5 -18.1 145.0 0.806 0.0 HOH
 3.865
 CG
 O
GLN C:157 C:151 148.0 0.822 T -66.2 -27.2 148.0 0.822 0.0 HOH
 8.184
 NE2
 O
GLN D:157 D:151 151.0 0.839 G -72.7 -3.3 151.0 0.839 0.0 HOH
 5.621
 NE2
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 GLN A:150 A:151 146.0 0.811 T -60.8 -29.2 146.0 0.811 0.0
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 GLN A:152 A:151 147.0 0.817 T -71.4 -12.5 147.0 0.817 0.0 HOH
 3.704
 O
 O
GLN B:152 B:151 124.0 0.689 G -69.1 -16.3 124.0 0.689 0.0 HOH
 2.864
 NE2
 O
GLN C:152 C:151 131.0 0.728 G -71.9 -6.2 131.0 0.728 0.0 HOH
 3.019
 NE2
 O
GLN D:152 D:151 147.0 0.817 G -71.4 -8.3 147.0 0.817 0.0 HOH
 2.865
 NE2
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 GLN A:158 A:151 131.0 0.728 G -69.1 -16.8 131.0 0.728 0.0 HOH
 3.688
 CG
 O
GLN B:158 B:151 125.0 0.694 G -64.9 -18.7 125.0 0.694 0.0 HOH
 2.453
 O
 O
GLN C:158 C:151 132.0 0.733 G -71.2 -2.0 132.0 0.733 0.0 HOH
 2.625
 OE1
 O
GLN D:158 D:151 137.0 0.761 G -71.3 -13.6 137.0 0.761 0.0 HOH
 2.563
 NE2
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 GLN A:152 A:151 119.0 0.661 T -61.4 -35.8 119.0 0.661 0.0 HOH
 3.285
 NE2
 O
GLN B:152 B:151 74.0 NA G -85.1 21.2 74.0 NA NA
GLN C:152 C:151 132.0 0.733 S -72.1 -35.6 132.0 0.733 0.0
GLN D:152 D:151 116.0 0.644 H -67.6 -29.4 116.0 0.644 0.0 HOH
 2.322
 NE2
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 GLN A:152 A:151 136.0 0.756 T -68.9 -24.6 136.0 0.756 0.0
GLN B:152 B:151 127.0 0.706 G -80.4 -18.6 127.0 0.706 0.0 HOH
 7.119
 N
 O
GLN C:152 C:151 132.0 0.733 H -68.1 -29.7 132.0 0.733 0.0 HOH
 3.784
 CG
 O
GLN D:152 D:151 128.0 0.711 G -68.6 -28.7 128.0 0.711 0.0 HOH
 5.109
 O
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 GLN A:149 A:151 131.0 0.728 G -71.4 -15.5 131.0 0.728 0.0 HOH
 2.792
 OE1
 O
GLN B:149 B:151 144.0 0.8 T -82.1 -12.8 144.0 0.8 0.0 HOH
 2.419
 NE2
 O
GLN C:149 C:151 138.0 0.767 T -61.7 -27.3 138.0 0.767 0.0 HOH
 2.297
 OE1
 O
GLN D:149 D:151 151.0 0.839 G -74.2 -10.2 151.0 0.839 0.0 HOH
 2.856
 NE2
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 GLN A:148 A:151 124.0 0.689 H -66.2 -62.2 124.0 0.689 0.0 HOH
 7.432
 N
 O
GLN B:148 B:151 171.0 0.95 S -170.1 -59.6 171.0 0.95 0.0
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 GLN A:160 A:160 133.0 0.739 T -75.3 -10.4 133.0 0.739 0.0 HOH
 3.439
 OE1
 O
GLN B:160 B:160 137.0 0.761 T -68.1 -20.2 137.0 0.761 0.0 HOH
 3.306
 NE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 GLN A:152 A:152 128.0 0.711 T -64.4 -22.9