Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133627616 . G A CCDS14641.1:NM_000194.2:c.481Gca>Aca_NP_000185.1:p.161A>T Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 ALA A:160 A:160 0.0 0.0 E -114.9 118.1 0.0 0.0 0.0 HOH
 7.571
 N
 O
ALA B:160 B:160 0.0 0.0 E -114.6 123.1 0.0 0.0 0.0 IMU
HOH
 9.869
7.433
 O
N
 O3'
O
ALA C:160 C:160 1.0 0.009 E -126.7 122.1 1.0 0.009 0.0 IMU
HOH
 9.948
7.796
 O
CA
 O3'
O
ALA D:160 D:160 0.0 0.0 E -120.3 120.5 0.0 0.0 0.0 HOH
 7.601
 CA
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 ALA A:160 A:160 1.0 0.009 E -127.8 114.5 1.0 0.009 0.0 HOH
 6.861
 O
 O
ALA B:160 B:160 2.0 0.017 E -95.3 140.5 2.0 0.017 0.0 HOH
 7.723
 N
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 ALA A:160 A:160 1.0 0.009 E -121.7 131.5 1.0 0.009 0.0 HOH
 7.426
 O
 O
ALA B:160 B:160 1.0 0.009 E -123.1 132.1 1.0 0.009 0.0 HOH
 7.347
 O
 O
ALA C:160 C:160 0.0 0.0 E -122.1 132.3 NA NA NA
ALA D:160 D:160 2.0 0.017 E -117.8 134.7 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ALA A:160 A:160 0.0 0.0 E -110.7 129.9 0.0 0.0 0.0 HOH
 6.673
 O
 O
ALA B:160 B:160 1.0 0.009 E -113.9 131.7 1.0 0.009 0.0 HOH
 6.632
 O
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ALA A:160 A:160 1.0 0.009 E -128.1 120.8 1.0 0.009 0.0 HOH
 6.394
 O
 O
ALA B:160 B:160 1.0 0.009 E -107.0 135.1 1.0 0.009 0.0 HOH
 8.067
 N
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ALA A:160 A:160 0.0 0.0 E -130.0 128.8 0.0 0.0 0.0 HOH
 6.395
 O
 O
ALA B:160 B:160 1.0 0.009 E -116.9 136.9 1.0 0.009 0.0 HOH
 6.872
 O
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ALA A:160 A:160 1.0 0.009 E -106.4 123.2 1.0 0.009 0.0 MG
HOH
 7.956
7.184
 O
N
 MG
O
ALA B:160 B:160 1.0 0.009 E -104.2 121.5 1.0 0.009 0.0 MG
HOH
 8.413
7.689
 O
O
 MG
O
ALA C:160 C:160 1.0 0.009 E -111.3 122.2 1.0 0.009 0.0 MG
HOH
 8.613
7.686
 O
CA
 MG
O
ALA D:160 D:160 1.0 0.009 E -111.1 122.1 1.0 0.009 0.0 MG
HOH
 8.902
7.757
 O
CA
 MG
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ALA A:160 A:160 1.0 0.009 E -111.4 127.7 1.0 0.009 0.0 MG
HOH
 8.719
7.685
 O
O
 MG
O
ALA B:160 B:160 0.0 0.0 E -113.4 128.8 0.0 0.0 0.0 MG
HOH
 8.473
7.824
 O
CA
 MG
O
ALA C:160 C:160 1.0 0.009 E -117.7 130.4 1.0 0.009 0.0 MG
HOH
 8.548
7.698
 O
CA
 MG
O
ALA D:160 D:160 0.0 0.0 E -107.9 127.8 0.0 0.0 0.0 MG
HOH
 8.853
8.704
 O
O
 MG
O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ALA A:160 A:160 0.0 0.0 E -111.9 130.2 0.0 0.0 0.0 MG
HOH
 7.528
7.052
 O
HA
 MG
O
ALA B:160 B:160 1.0 0.009 E -107.2 129.7 1.0 0.009 0.0 MG
HOH
 7.589
7.047
 O
HA
 MG
O
ALA C:160 C:160 0.0 0.0 E -114.3 125.4 0.0 0.0 0.0 MG
HOH
 8.552
7.015
 O
N
 MG
O
ALA D:160 D:160 0.0 0.0 E -110.7 126.4 0.0 0.0 0.0 MG
HOH
 8.997
6.741
 O
HA
 MG
O
ALA E:160 E:160 0.0 0.0 E -108.2 130.5 NA NA NA
ALA F:160 F:160 0.0 0.0 E -109.7 132.9 NA NA NA
ALA G:160 G:160 0.0 0.0 E -114.8 128.7 NA NA NA
ALA H:160 H:160 0.0 0.0 E -111.8 130.9 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ALA A:160 A:160 0.0 0.0 E -113.4 121.7 0.0 0.0 0.0 MG
HOH
 9.130
7.566
 O
CA
 MG
O
ALA B:160 B:160 1.0 0.009 E -113.9 117.2 1.0 0.009 0.0 MG
HOH
 9.424
7.057
 O
N
 MG
O
ALA C:160 C:160 0.0 0.0 E -103.7 124.4 0.0 0.0 0.0 MG
 8.959
 O
 MG
ALA D:160 D:160 0.0 0.0 E -107.9 120.7 0.0 0.0 0.0 MG
 9.239
 O
 MG
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ALA A:160 A:160 1.0 0.009 E -106.7 126.5 1.0 0.009 0.0 MG
HOH
 8.828
7.211
 O
N
 MG
O
ALA B:160 B:160 1.0 0.009 E -113.7 130.1 1.0 0.009 0.0 MG
HOH
 8.542
7.669
 O
CA
 MG
O
ALA C:160 C:160 0.0 0.0 E -111.0 128.1 0.0 0.0 0.0 MG
HOH
 8.724
7.605
 O
CA
 MG
O
ALA D:160 D:160 0.0 0.0 E -110.4 128.7 0.0 0.0 0.0 MG
HOH
 8.827
7.316
 O
N
 MG
O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ALA A:160 A:160 0.0 0.0 E -108.3 123.7 0.0 0.0 0.0 MG
HOH
 9.506
7.454
 O
CA
 MG
O
ALA B:160 B:160 0.0 0.0 E -112.4 129.6 0.0 0.0 0.0 MG
HOH
 9.494
8.922
 O
O
 MG
O
ALA C:160 C:160 1.0 0.009 E -114.9 127.8 1.0 0.009 0.0 MG
HOH
 8.485
9.231
 O
O
 MG
O
ALA D:160 D:160 0.0 0.0 E -112.5 121.2 0.0 0.0 0.0 MG
HOH
 9.643
6.936
 O
N
 MG
O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 ALA A:166 A:160 1.0 0.009 E -116.1 128.1 1.0 0.009 0.0 MG
HOH
 8.637
6.955
 O
N
 MG
O
ALA B:166 B:160 1.0 0.009 E -107.7 131.8 1.0 0.009 0.0 MG
HOH
 8.655
7.357
 O
N
 MG
O
ALA C:166 C:160 0.0 0.0 E -109.5 127.1 0.0 0.0 0.0 MG
HOH
 8.601
6.911
 O
N
 MG
O
ALA D:166 D:160 0.0 0.0 E -106.5 132.6 0.0 0.0 0.0 MG
HOH
 8.804
7.844
 O
CA
 MG
O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 ALA A:159 A:160 0.0 0.0 E -119.5 132.4 0.0 0.0 0.0 HOH
 6.907
 O
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 ALA A:161 A:160 0.0 0.0 E -111.1 126.9 0.0 0.0 0.0 MG
HOH
 8.755
7.076
 O
N
 MG
O
ALA B:161 B:160 1.0 0.009 E -108.0 122.8 1.0 0.009 0.0 MG
HOH
 8.888
7.026
 O
N
 MG
O
ALA C:161 C:160 0.0 0.0 E -112.2 127.3 0.0 0.0 0.0 MG
HOH
 8.606
7.058
 O
N
 MG
O
ALA D:161 D:160 0.0 0.0 E -105.5 125.6 0.0 0.0 0.0 MG
HOH
 8.675
7.679
 O
CA
 MG
O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 ALA A:167 A:160 1.0 0.009 E -107.1 128.2 1.0 0.009 0.0 MG
HOH
 8.727
7.336
 O
N
 MG
O
ALA B:167 B:160 1.0 0.009 E -112.4 127.3 1.0 0.009 0.0 MG
HOH
 8.665
6.942
 O
N
 MG
O
ALA C:167 C:160 0.0 0.0 E -108.9 128.0 0.0 0.0 0.0 MG
HOH
 8.629
7.014
 O
N
 MG
O
ALA D:167 D:160 0.0 0.0 E -115.6 126.3 0.0 0.0 0.0 MG
HOH
 8.687
6.844
 O
N
 MG
O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 ALA A:161 A:160 1.0 0.009 E -99.5 119.2 1.0 0.009 0.0 MG
HOH
 8.827
7.703
 O
CA
 MG
O
ALA B:161 B:160 1.0 0.009 E -105.4 113.9 1.0 0.009 0.0 MG
HOH
 8.889
7.818
 O
CA
 MG
O
ALA C:161 C:160 0.0 0.0 E -108.4 116.9 0.0 0.0 0.0 MG
HOH
 9.058
7.084
 O
N
 MG
O
ALA D:161 D:160 1.0 0.009 E -109.0 122.4 1.0 0.009 0.0 MG
HOH
 8.734
7.239
 O
N
 MG
O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 ALA A:161 A:160 1.0 0.009 E -114.8 120.0 1.0 0.009 0.0 MG
HOH
 9.071
7.656
 O
CA
 MG
O
ALA B:161 B:160 2.0 0.017 E -110.3 114.6 2.0 0.017 0.0 MG
HOH
 9.055
8.554
 O
O
 MG
O
ALA C:161 C:160 0.0 0.0 E -111.3 115.4 0.0 0.0 0.0 MG
HOH
 9.025
7.163
 O
N
 MG
O
ALA D:161 D:160 1.0 0.009 E -108.6 114.1 1.0 0.009 0.0 MG
HOH
 9.038
9.194
 O
O
 MG
O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 ALA A:158 A:160 1.0 0.009 E -109.1 124.9 1.0 0.009 0.0 MG
HOH
 8.705
6.920
 O
N
 MG
O
ALA B:158 B:160 1.0 0.009 E -114.6 114.2 1.0 0.009 0.0 MG
HOH
 8.662
6.738
 O
N
 MG
O
ALA C:158 C:160 1.0 0.009 E -106.3 116.1 1.0 0.009 0.0 MG
HOH
 8.729
7.048
 O
N
 MG
O
ALA D:158 D:160 1.0 0.009 E -114.3 129.2 1.0 0.009 0.0 MG
HOH
 8.667
6.585
 O
N
 MG
O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 ALA A:157 A:160 1.0 0.009 -158.5 132.0 1.0 0.009 0.0 MG
PRP
HOH
 7.682
8.356
7.165
 O
O
O
 MG
O3
O
ALA B:157 B:160 1.0 0.009 E -82.2 149.6 1.0 0.009 0.0 MG
HOH
 9.140
9.275
 O
O
 MG
O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 ALA A:169 A:169 1.0 0.009 E -102.9 139.8 1.0 0.009 0.0 HOH
 7.581
 N
 O
ALA B:169 B:169 1.0 0.009 E -112.2 142.6 1.0 0.009 0.0 SO4
HOH
 9.262
7.363
 O
CA
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 ALA A:161 A:161 0.0 0.0 E -104.7 129.5