Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133632437 . C A CCDS14641.1:NM_000194.2:c.503aCc>aAc_NP_000185.1:p.168T>N Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 THR A:167 A:167 15.0 0.107 -144.2 143.4 15.0 0.107 0.0 IMU
HOH
 7.479
4.322
 CG2
CG2
 O3P
O
THR B:167 B:167 17.0 0.121 -141.7 147.3 17.0 0.121 0.0 IMU
HOH
 7.471
3.114
 CG2
OG1
 O3P
O
THR C:167 C:167 16.0 0.114 -148.0 145.1 16.0 0.114 0.0 IMU
HOH
 7.440
4.376
 CG2
CG2
 O3P
O
THR D:167 D:167 17.0 0.121 -144.9 143.6 17.0 0.121 0.0 IMU
HOH
 7.466
4.087
 CG2
CG2
 O1P
O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 THR A:167 A:167 21.0 0.15 -152.3 154.7 21.0 0.15 0.0 5GP
HOH
 8.203
3.510
 OG1
CA
 O1P
O
THR B:167 B:167 16.0 0.114 -128.2 148.5 16.0 0.114 0.0 5GP
HOH
 7.492
4.313
 OG1
OG1
 O2P
O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 THR A:167 A:167 136.0 NA 51.9 360.0 136.0 NA NA HOH
 3.041
 CB
 O
THR B:167 B:167 61.0 0.436 -69.0 143.7 61.0 0.436 0.0 HOH
 4.604
 CG2
 O
THR C:167 C:167 16.0 0.114 -126.4 152.3 NA NA NA
THR D:167 D:167 64.0 0.457 -109.3 126.5 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 THR A:167 A:167 14.0 0.1 -117.6 138.9 14.0 0.1 0.0 24H
HOH
 7.372
3.598
 OG1
CG2
 N7
O
THR B:167 B:167 40.0 0.286 -116.4 150.7 40.0 0.286 0.0 24H
HOH
 7.423
4.010
 OG1
O
 N7
O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 THR A:167 A:167 17.0 0.121 -127.4 143.1 17.0 0.121 0.0 H26
HOH
 7.670
4.492
 OG1
OG1
 OAD
O
THR B:167 B:167 39.0 0.279 S -135.9 173.8 39.0 0.279 0.0 H26
HOH
 7.662
4.390
 OG1
O
 N7
O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 THR A:167 A:167 14.0 0.1 -128.0 139.4 14.0 0.1 0.0 25H
HOH
 7.570
3.587
 OG1
CG2
 OAD
O
THR B:167 B:167 44.0 0.314 -136.4 164.2 44.0 0.314 0.0 25H
HOH
 7.449
4.564
 OG1
O
 N7
O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:167 A:167 16.0 0.114 -162.7 134.8 16.0 0.114 0.0 3L3
HOH
 7.468
5.728
 CG2
N
 OAC
O
THR B:167 B:167 41.0 0.293 S -162.1 163.9 41.0 0.293 0.0 3L3
HOH
 6.531
9.115
 CG2
CG2
 OAE
O
THR C:167 C:167 17.0 0.121 -151.9 139.6 17.0 0.121 0.0 3L3
HOH
 7.327
9.649
 CG2
CG2
 OAC
O
THR D:167 D:167 17.0 0.121 -142.5 150.1 17.0 0.121 0.0 3L3
HOH
 7.022
5.528
 CG2
N
 OAC
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:167 A:167 30.0 0.214 S -155.0 155.5 30.0 0.214 0.0 3L4
HOH
 7.453
3.280
 CG2
OG1
 OAC
O
THR B:167 B:167 27.0 0.193 -147.8 142.7 27.0 0.193 0.0 3L4
HOH
 7.594
3.922
 CG2
CG2
 OAF
O
THR C:167 C:167 14.0 0.1 -137.6 133.6 14.0 0.1 0.0 3L4
HOH
 7.055
6.789
 CG2
N
 OAF
O
THR D:167 NA:NA DO NA DO DO DO NA NA NA
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:167 A:167 17.0 0.121 -135.8 147.3 17.0 0.121 0.0 3L5
HOH
 6.056
3.573
 HG1
H
 H25
O
THR B:167 B:167 32.0 0.229 S -149.7 147.7 32.0 0.229 0.0 3L5
HOH
 6.342
6.041
 HG21
HA
 H25
O
THR C:167 C:167 19.0 0.136 -164.7 140.4 19.0 0.136 0.0 3L5
HOH
 6.584
3.852
 HG21
HG22
 H25
O
THR D:167 D:167 18.0 0.129 -140.8 143.1 18.0 0.129 0.0 3L5
HOH
 6.624
3.498
 HG21
HG22
 OAD
O
THR E:167 E:167 35.0 0.25 -136.8 165.0 NA NA NA
THR F:167 F:167 26.0 0.186 S -139.8 162.7 NA NA NA
THR G:167 G:167 41.0 0.293 -126.2 134.2 NA NA NA
THR H:167 H:167 19.0 0.136 -151.5 145.1 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:167 A:167 18.0 0.129 -149.5 143.0 18.0 0.129 0.0 3L6
HOH
 7.234
2.990
 CG2
OG1
 OAE
O
THR B:167 B:167 17.0 0.121 -143.7 144.6 17.0 0.121 0.0 3L6
 7.024
 CG2
 OAE
THR C:167 C:167 14.0 0.1 -130.5 146.7 14.0 0.1 0.0 3L6
 7.093
 CG2
 OAE
THR D:167 D:167 21.0 0.15 -153.4 145.5 21.0 0.15 0.0 3L6
 7.250
 CG2
 OAF
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:167 A:167 16.0 0.114 -145.2 137.1 16.0 0.114 0.0 3L7
HOH
 7.432
4.157
 CG2
CG2
 OAF
O
THR B:167 B:167 31.0 0.221 S -153.3 150.4 31.0 0.221 0.0 3L7
HOH
 7.262
6.226
 CG2
N
 OAF
O
THR C:167 C:167 20.0 0.143 -153.9 145.5 20.0 0.143 0.0 3L7
HOH
 7.340
2.904
 CG2
OG1
 OAC
O
THR D:167 D:167 18.0 0.129 -147.0 144.4 18.0 0.129 0.0 3L7
HOH
 7.301
6.304
 CG2
OG1
 OAG
O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:167 A:167 19.0 0.136 -149.5 139.3 19.0 0.136 0.0 3L8
HOH
 6.863
4.539
 CG2
O
 OAB
O
THR B:167 B:167 16.0 0.114 -154.0 136.9 16.0 0.114 0.0 3L8
HOH
 7.086
2.626
 CG2
OG1
 OAE
O
THR C:167 C:167 30.0 0.214 -123.9 151.3 30.0 0.214 0.0 3L8
HOH
 7.060
6.030
 CG2
N
 OAB
O
THR D:167 D:167 13.0 0.093 -132.8 146.2 13.0 0.093 0.0 3L8
HOH
 7.188
5.338
 CG2
CG2
 OAB
O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 THR A:173 A:167 19.0 0.136 -157.3 139.3 19.0 0.136 0.0 SV2
HOH
 7.392
2.675
 CG2
OG1
 OAG
O
THR B:173 B:167 17.0 0.121 -145.8 146.5 17.0 0.121 0.0 SV2
HOH
 7.165
4.347
 CG2
CG2
 OAD
O
THR C:173 C:167 17.0 0.121 -147.6 138.4 17.0 0.121 0.0 SV2
HOH
 7.185
3.492
 CG2
OG1
 OAG
O
THR D:173 D:167 20.0 0.143 -154.3 141.1 20.0 0.143 0.0 SV2
HOH
 7.235
2.586
 CG2
OG1
 OAG
O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 THR A:166 A:167 18.0 0.129 -160.4 142.0 18.0 0.129 0.0 1RP
HOH
 6.721
5.720
 HG21
HG1
 OAC
O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 THR A:168 A:167 19.0 0.136 -157.7 138.3 19.0 0.136 0.0 WPG
HOH
 7.654
3.108
 CG2
OG1
 OAE
O
THR B:168 B:167 17.0 0.121 -154.7 138.5 17.0 0.121 0.0 WPG
HOH
 7.497
2.812
 CG2
OG1
 OAE
O
THR C:168 C:167 16.0 0.114 -139.0 142.5 16.0 0.114 0.0 WPG
HOH
 7.278
2.842
 CG2
OG1
 OAE
O
THR D:168 D:167 13.0 0.093 -148.4 145.2 13.0 0.093 0.0 WPG
HOH
 7.597
2.526
 CG2
OG1
 OAJ
O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 THR A:174 A:167 21.0 0.15 -151.4 145.0 21.0 0.15 0.0 YPG
HOH
 7.353
3.091
 CG2
N
 OAJ
O
THR B:174 B:167 18.0 0.129 -148.6 139.2 18.0 0.129 0.0 YPG
HOH
 7.322
2.387
 CG2
OG1
 OAJ
O
THR C:174 C:167 18.0 0.129 -143.4 141.7 18.0 0.129 0.0 YPG
HOH
 7.359
2.997
 CG2
OG1
 OAJ
O
THR D:174 D:167 20.0 0.143 -150.2 143.2 20.0 0.143 0.0 YPG
HOH
 7.386
5.452
 CG2
CA
 OAJ
O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 THR A:168 A:167 18.0 0.129 -146.6 142.6 18.0 0.129 0.0 4X2
HOH
 7.298
3.239
 CG2
N
 O03
O
THR B:168 NA:NA DO NA DO DO DO NA NA NA
THR C:168 C:167 16.0 0.114 -137.7 144.6 16.0 0.114 0.0 4X2
HOH
 7.198
2.782
 CG2
OG1
 O01
O
THR D:168 D:167 20.0 0.143 -123.3 140.6 20.0 0.143 0.0 4X2
HOH
 6.827
3.721
 CG2
N
 O01
O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 THR A:168 A:167 15.0 0.107 -122.8 144.0 15.0 0.107 0.0 4X7
HOH
 7.268
6.402
 CG2
OG1
 OAE
O
THR B:168 B:167 17.0 0.121 -131.2 141.2 17.0 0.121 0.0 4X7
HOH
 7.370
4.456
 CG2
OG1
 OAF
O
THR C:168 C:167 14.0 0.1 -143.7 145.2 14.0 0.1 0.0 4X7
HOH
 7.541
4.381
 CG2
CG2
 OAC
O
THR D:168 D:167 90.0 0.643 -116.0 360.0 90.0 0.643 0.0 4X7
HOH
 6.834
4.864
 CG2
N
 N7
O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 THR A:165 A:167 18.0 0.129 -144.4 143.5 18.0 0.129 0.0 9YP
HOH
 7.486
3.055
 CG2
N
 OAD
O
THR B:165 B:167 43.0 0.307 S -163.6 153.8 43.0 0.307 0.0 9YP
HOH
 7.662
3.019
 CG2
N
 OAH
O
THR C:165 C:167 16.0 0.114 -134.4 141.0 16.0 0.114 0.0 9YP
HOH
 7.402
3.079
 CG2
OG1
 OAD
O
THR D:165 D:167 22.0 0.157 -155.0 138.5 22.0 0.157 0.0 9YP
HOH
 7.524
2.824
 CG2
OG1
 OAG
O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 THR A:164 A:167 14.0 0.1 -154.5 160.6 14.0 0.1 0.0 PPO
PRP
HOH
 9.277
8.241
9.410
 CB
CG2
O
 N7
O2P
O
THR B:164 B:167 2.0 0.014 -65.8 134.3 2.0 0.014 0.0 PPO
PRP
HOH
 8.665
6.030
5.933
 CB
CG2
O
 C9
O1P
O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 THR A:176 A:176 14.0 0.1 -78.0 132.7 14.0 0.1 0.0 5GP
SO4
HOH
 8.144
7.499
9.230
 OG1
OG1
CG2
 N7
O4
O
THR B:176 B:176 23.0 0.164 -132.3 138.8 23.0 0.164 0.0 5GP
SO4
HOH
 8.132
8.223
6.680
 OG1
OG1
OG1
 N7
O2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 THR A:168 A:168 14.0 0.1 -132.0 142.1