Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133632439 . C A CCDS14641.1:NM_000194.2:c.505Cca>Aca_NP_000185.1:p.169P>T Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 PRO A:168 A:168 120.0 0.828 T -62.8 -28.6 120.0 0.828 0.0 HOH
 4.942
 CD
 O
PRO B:168 B:168 120.0 0.828 T -65.6 -19.1 120.0 0.828 0.0 HOH
 5.759
 CD
 O
PRO C:168 C:168 125.0 0.862 T -62.8 -23.9 125.0 0.862 0.0 HOH
 6.475
 CD
 O
PRO D:168 D:168 124.0 0.855 T -60.4 -27.4 124.0 0.855 0.0 HOH
 7.218
 CD
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 PRO A:168 A:168 126.0 0.869 T -79.5 -16.7 126.0 0.869 0.0 HOH
 3.001
 CD
 O
PRO B:168 B:168 115.0 0.793 T -65.5 -22.3 115.0 0.793 0.0 HOH
 5.912
 CD
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 PRO A:168 NA:NA DO NA DO DO DO NA NA NA
PRO B:168 B:168 113.0 0.779 S -67.7 -14.9 113.0 0.779 0.0 HOH
 6.119
 CD
 O
PRO C:168 C:168 135.0 0.931 T -70.5 13.1 NA NA NA
PRO D:168 D:168 133.0 0.917 -69.0 -16.4 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 PRO A:168 A:168 127.0 0.876 T -57.4 -23.0 127.0 0.876 0.0 HOH
 3.566
 CD
 O
PRO B:168 B:168 122.0 0.841 -71.3 131.0 122.0 0.841 0.0 24H
HOH
 9.053
2.321
 O
O
 OAE
O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 PRO A:168 A:168 122.0 0.841 T -58.8 -37.6 122.0 0.841 0.0 HOH
 3.564
 CD
 O
PRO B:168 B:168 113.0 0.779 -57.6 86.2 113.0 0.779 0.0 H26
HOH
 8.656
3.984
 O
O
 OAD
O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 PRO A:168 A:168 128.0 0.883 T -59.2 -22.2 128.0 0.883 0.0 HOH
 3.851
 CD
 O
PRO B:168 B:168 114.0 0.786 -61.4 121.7 114.0 0.786 0.0 25H
HOH
 8.217
3.249
 O
CB
 OAD
O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:168 A:168 138.0 0.952 T -64.0 -11.8 138.0 0.952 0.0 HOH
 2.764
 O
 O
PRO B:168 B:168 114.0 0.786 -63.6 120.4 114.0 0.786 0.0 3L3
HOH
 6.934
9.582
 O
O
 OAE
O
PRO C:168 C:168 134.0 0.924 T -71.5 12.5 134.0 0.924 0.0
PRO D:168 D:168 127.0 0.876 T -69.4 -26.9 127.0 0.876 0.0 3L3
HOH
 9.760
6.587
 C
CD
 OAC
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:168 A:168 120.0 0.828 -65.4 130.5 120.0 0.828 0.0 3L4
HOH
 8.464
3.808
 O
CD
 OAC
O
PRO B:168 B:168 122.0 0.841 S -72.3 -25.2 122.0 0.841 0.0 HOH
 3.636
 CD
 O
PRO C:168 C:168 122.0 0.841 T -66.7 -15.1 122.0 0.841 0.0 HOH
 7.295
 CD
 O
PRO D:168 NA:NA DO NA DO DO DO NA NA NA
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:168 A:168 118.0 0.814 T -60.0 -32.0 118.0 0.814 0.0 3L5
HOH
 9.299
5.577
 HD2
HD3
 H25
O
PRO B:168 B:168 121.0 0.834 -57.2 137.2 121.0 0.834 0.0 3L5
HOH
 8.351
7.612
 O
HD3
 OAD
O
PRO C:168 C:168 137.0 0.945 T -62.1 -13.4 137.0 0.945 0.0 HOH
 5.703
 O
 O
PRO D:168 D:168 114.0 0.786 S -64.6 -19.4 114.0 0.786 0.0 HOH
 5.968
 HD3
 O
PRO E:168 E:168 170.0 1.0 -59.0 360.0 NA NA NA
PRO F:168 F:168 119.0 0.821 -60.4 112.2 NA NA NA
PRO G:168 G:168 133.0 0.917 -67.9 114.6 NA NA NA
PRO H:168 H:168 127.0 0.876 T -67.0 -25.7 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:168 A:168 128.0 0.883 T -67.3 -18.9 128.0 0.883 0.0 HOH
 5.903
 CD
 O
PRO B:168 B:168 126.0 0.869 T -66.5 -15.7 126.0 0.869 0.0
PRO C:168 C:168 120.0 0.828 T -63.6 -30.5 120.0 0.828 0.0
PRO D:168 D:168 120.0 0.828 T -76.0 -5.9 120.0 0.828 0.0
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:168 A:168 137.0 0.945 T -61.6 -18.8 137.0 0.945 0.0 HOH
 7.421
 N
 O
PRO B:168 B:168 120.0 0.828 -56.6 137.4 120.0 0.828 0.0 3L7
HOH
 8.130
8.257
 O
CD
 OAF
O
PRO C:168 C:168 135.0 0.931 T -69.3 -12.2 135.0 0.931 0.0 HOH
 3.760
 CD
 O
PRO D:168 D:168 128.0 0.883 T -68.3 -22.5 128.0 0.883 0.0 HOH
 8.909
 CD
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:168 A:168 127.0 0.876 T -67.0 -8.9 127.0 0.876 0.0 HOH
 4.173
 O
 O
PRO B:168 B:168 136.0 0.938 T -56.0 -33.3 136.0 0.938 0.0 HOH
 5.654
 CD
 O
PRO C:168 C:168 127.0 0.876 -55.1 -41.3 127.0 0.876 0.0 3L8
HOH
 9.903
6.987
 C
C
 OAB
O
PRO D:168 D:168 127.0 0.876 T -67.8 -16.0 127.0 0.876 0.0 HOH
 8.172
 N
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 PRO A:174 A:168 136.0 0.938 T -65.1 -16.0 136.0 0.938 0.0 HOH
 5.719
 N
 O
PRO B:174 B:168 126.0 0.869 T -72.5 -8.1 126.0 0.869 0.0 HOH
 7.938
 N
 O
PRO C:174 C:168 122.0 0.841 T -67.5 -13.4 122.0 0.841 0.0 HOH
 2.946
 CG
 O
PRO D:174 D:168 133.0 0.917 T -75.2 -11.2 133.0 0.917 0.0 HOH
 5.310
 CD
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 PRO A:167 A:168 128.0 0.883 T -67.9 -11.0 128.0 0.883 0.0 HOH
 7.903
 HD2
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 PRO A:169 A:168 128.0 0.883 T -72.1 -6.2 128.0 0.883 0.0 HOH
 2.648
 O
 O
PRO B:169 B:168 130.0 0.897 T -58.2 -21.2 130.0 0.897 0.0 HOH
 5.610
 O
 O
PRO C:169 C:168 123.0 0.848 T -72.3 -7.8 123.0 0.848 0.0 HOH
 3.482
 CD
 O
PRO D:169 D:168 121.0 0.834 T -76.8 -5.6 121.0 0.834 0.0 HOH
 2.538
 O
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 PRO A:175 A:168 121.0 0.834 T -69.0 -13.7 121.0 0.834 0.0 HOH
 2.788
 O
 O
PRO B:175 B:168 128.0 0.883 T -69.8 -8.4 128.0 0.883 0.0 HOH
 3.113
 CD
 O
PRO C:175 C:168 124.0 0.855 T -69.3 -7.3 124.0 0.855 0.0 HOH
 4.556
 CD
 O
PRO D:175 D:168 123.0 0.848 T -71.3 -7.7 123.0 0.848 0.0 HOH
 4.114
 CD
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 PRO A:169 A:168 129.0 0.89 T -71.8 -12.0 129.0 0.89 0.0 HOH
 2.303
 O
 O
PRO B:169 NA:NA DO NA DO DO DO NA NA NA
PRO C:169 C:168 127.0 0.876 T -74.9 4.5 127.0 0.876 0.0 HOH
 2.164
 O
 O
PRO D:169 D:168 124.0 0.855 T -54.8 -30.0 124.0 0.855 0.0 HOH
 6.530
 N
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 PRO A:169 A:168 124.0 0.855 T -69.8 -9.5 124.0 0.855 0.0 HOH
 8.082
 CD
 O
PRO B:169 B:168 123.0 0.848 T -66.3 -15.8 123.0 0.848 0.0 HOH
 3.857
 CD
 O
PRO C:169 C:168 128.0 0.883 T -71.2 -7.2 128.0 0.883 0.0 HOH
 5.525
 O
 O
PRO D:169 NA:NA DO NA DO DO DO NA NA NA
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 PRO A:166 A:168 128.0 0.883 T -70.1 -14.4 128.0 0.883 0.0 HOH
 5.108
 N
 O
PRO B:166 B:168 127.0 0.876 S -56.3 98.2 127.0 0.876 0.0 9YP
HOH
 8.758
2.453
 O
O
 OAH
O
PRO C:166 C:168 126.0 0.869 T -69.7 -11.2 126.0 0.869 0.0 HOH
 5.255
 CD
 O
PRO D:166 D:168 136.0 0.938 T -65.4 -23.0 136.0 0.938 0.0 HOH
 5.248
 CD
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 PRO A:165 A:168 119.0 0.821 S -67.5 -46.1 119.0 0.821 0.0 HOH
 9.950
 O
 O
PRO B:165 B:168 109.0 0.752 T -64.6 -21.9 109.0 0.752 0.0 PRP
HOH
 9.497
6.995
 C
C
 O1P
O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 PRO A:177 A:177 120.0 0.828 T -56.0 -32.5 120.0 0.828 0.0 HOH
 9.485
 CD
 O
PRO B:177 B:177 127.0 0.876 T -55.8 -16.0 127.0 0.876 0.0 HOH
 9.681
 CD
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 PRO A:169 A:169 132.0 0.91 T -64.1 -14.7