Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133632442 . C A CCDS14641.1:NM_000194.2:c.508Cga>Aga_NP_000185.1:p.170R>R Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 ARG A:169 A:169 112.0 0.498 T -69.0 -17.5 112.0 0.498 0.0 IMU
HOH
 6.599
3.579
 NH2
NH2
 N7
O
ARG B:169 B:169 114.0 0.507 T -81.6 -11.3 114.0 0.507 0.0 IMU
HOH
 7.131
2.423
 O
NH2
 O3P
O
ARG C:169 C:169 119.0 0.529 T -72.8 -25.8 119.0 0.529 0.0 IMU
HOH
 6.245
6.513
 NH2
C
 N7
O
ARG D:169 D:169 113.0 0.502 T -69.6 -16.2 113.0 0.502 0.0 IMU
HOH
 6.188
3.197
 NH2
NH2
 N7
O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 ARG A:169 A:169 133.0 0.591 T -85.4 12.8 133.0 0.591 0.0 5GP
HOH
 6.231
6.451
 NH2
NH2
 N7
O
ARG B:169 B:169 149.0 0.662 T -83.6 9.6 149.0 0.662 0.0 5GP
HOH
 6.920
6.075
 O
O
 O2P
O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 ARG A:169 NA:NA DO NA DO DO DO NA NA NA
ARG B:169 B:169 68.0 NA S -72.7 -158.4 68.0 NA NA HOH
 7.248
 CB
 O
ARG C:169 C:169 56.0 NA T -113.0 -7.0 NA NA NA
ARG D:169 D:169 122.0 NA -58.7 360.0 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:169 A:169 122.0 0.542 T -74.9 -6.5 122.0 0.542 0.0 24H
HOH
 5.212
3.320
 NH2
NH2
 OAF
O
ARG B:169 B:169 49.0 NA -136.4 166.2 49.0 NA NA 24H
HOH
 9.049
3.304
 CA
CA
 OAC
O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:169 A:169 126.0 0.56 T -61.5 -4.4 126.0 0.56 0.0 H26
HOH
 5.631
2.687
 NH2
NH2
 OAD
O
ARG B:169 B:169 61.0 NA -71.8 130.8 61.0 NA NA H26
HOH
 8.832
4.458
 CA
CA
 OAC
O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:169 A:169 120.0 0.533 T -77.7 -3.0 120.0 0.533 0.0 25H
HOH
 5.534
2.930
 NH2
NH1
 OAD
O
ARG B:169 B:169 51.0 NA -140.6 163.4 51.0 NA NA 25H
HOH
 8.604
3.861
 CA
N
 OAC
O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:169 A:169 113.0 0.502 T -73.8 -6.5 113.0 0.502 0.0 3L3
HOH
 5.743
2.785
 NH1
O
 OAC
O
ARG B:169 B:169 67.0 0.298 -129.4 104.3 67.0 0.298 0.0 3L3
HOH
 5.536
6.579
 NE
CD
 OAC
O
ARG C:169 C:169 151.0 0.671 T -111.4 -4.5 151.0 0.671 0.0 3L3
HOH
 5.123
9.530
 NH2
O
 BR8
O
ARG D:169 D:169 155.0 0.689 T -64.3 -3.9 155.0 0.689 0.0 3L3
HOH
 4.792
3.161
 NH2
NH1
 BR8
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:169 A:169 61.0 0.271 -120.1 142.6 61.0 0.271 0.0 3L4
HOH
 6.189
3.693
 CD
CA
 OAF
O
ARG B:169 B:169 124.0 0.551 S -71.0 68.5 124.0 0.551 0.0 3L4
HOH
 5.657
4.533
 NH2
NH2
 N7
O
ARG C:169 C:169 121.0 0.538 T -75.1 7.9 121.0 0.538 0.0 3L4
HOH
 5.365
4.201
 NH1
NH1
 OAF
O
ARG D:169 D:169 185.0 0.822 360.0 45.3 185.0 0.822 0.0 3L4
HOH
 5.566
4.610
 NH1
N
 OAC
O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:169 A:169 115.0 0.511 T -37.8 -55.2 115.0 0.511 0.0 3L5
HOH
 4.011
2.360
 HH21
HH22
 H25
O
ARG B:169 B:169 68.0 0.302 -142.2 126.7 68.0 0.302 0.0 3L5
MG
HOH
 5.294
9.006
5.361
 HD3
HD2
HH11
 OAH
MG
O
ARG C:169 C:169 105.0 0.467 T -72.0 -14.5 105.0 0.467 0.0 3L5
HOH
 4.149
2.670
 HH12
O
 H25
O
ARG D:169 D:169 169.0 0.751 -86.7 76.2 169.0 0.751 0.0 3L5
HOH
 6.308
5.078
 O
O
 OAD
O
ARG E:169 NA:NA DO NA DO DO DO NA NA NA
ARG F:169 F:169 117.0 0.52 -147.6 360.0 NA NA NA
ARG G:169 G:169 98.0 NA 151.7 360.0 NA NA NA
ARG H:169 H:169 158.0 0.702 T -65.2 -15.9 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:169 A:169 139.0 0.618 T -73.4 -10.2 139.0 0.618 0.0 3L6
HOH
 5.186
2.264
 NH2
NH1
 OAE
O
ARG B:169 B:169 136.0 0.604 T -91.5 10.1 136.0 0.604 0.0 3L6
 5.146
 NH2
 OAE
ARG C:169 C:169 144.0 0.64 T -68.2 -10.5 144.0 0.64 0.0 3L6
 6.739
 NH1
 N7
ARG D:169 D:169 129.0 0.573 T -96.7 14.8 129.0 0.573 0.0 3L6
 5.718
 NH2
 N7
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:169 A:169 138.0 0.613 T -71.6 -9.4 138.0 0.613 0.0 3L7
HOH
 5.351
6.357
 NH2
C
 OAF
O
ARG B:169 B:169 88.0 0.391 -141.6 103.0 88.0 0.391 0.0 3L7
HOH
 5.901
6.573
 NE
CD
 OAC
O
ARG C:169 C:169 143.0 0.636 T -83.3 -11.4 143.0 0.636 0.0 3L7
HOH
 5.280
2.732
 NH2
NE
 OAC
O
ARG D:169 D:169 131.0 0.582 T -75.7 4.3 131.0 0.582 0.0 3L7
HOH
 5.903
3.144
 NH1
NH2
 OAG
O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:169 A:169 112.0 0.498 T -92.5 -7.9 112.0 0.498 0.0 3L8
HOH
 4.732
3.654
 NH2
NH2
 OAB
O
ARG B:169 B:169 151.0 0.671 T -59.9 -9.9 151.0 0.671 0.0 3L8
HOH
 5.408
2.612
 NH1
NH1
 OAE
O
ARG C:169 C:169 49.0 NA -63.7 360.0 49.0 NA NA 3L8
HOH
 6.781
3.846
 CB
CB
 OAB
O
ARG D:169 D:169 147.0 0.653 T -78.9 -3.5 147.0 0.653 0.0 3L8
HOH
 5.312
6.367
 NH2
O
 OAB
O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 ARG A:175 A:169 144.0 0.64 T -77.9 -3.4 144.0 0.64 0.0 SV2
HOH
 5.702
2.786
 NH1
NH1
 OAG
O
ARG B:175 B:169 136.0 0.604 T -90.0 -1.7 136.0 0.604 0.0 SV2
HOH
 5.243
3.365
 NH2
NH2
 OAD
O
ARG C:175 C:169 112.0 0.498 T -83.2 1.8 112.0 0.498 0.0 SV2
HOH
 5.255
2.335
 NH1
NE
 OAG
O
ARG D:175 D:169 149.0 0.662 T -80.3 5.0 149.0 0.662 0.0 SV2
HOH
 5.999
2.853
 NH2
NH2
 C8
O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 ARG A:168 A:169 135.0 0.6 T -81.6 -4.9 135.0 0.6 0.0 1RP
HOH
 5.045
4.275
 HH22
HH12
 OAC
O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 ARG A:170 A:169 140.0 0.622 T -84.0 -5.9 140.0 0.622 0.0 WPG
HOH
 6.032
2.278
 NH1
NH1
 OAE
O
ARG B:170 B:169 142.0 0.631 T -83.5 -2.4 142.0 0.631 0.0 WPG
HOH
 5.051
2.513
 NH2
O
 OAE
O
ARG C:170 C:169 144.0 0.64 T -92.7 5.8 144.0 0.64 0.0 WPG
HOH
 5.894
2.554
 NH2
O
 OAE
O
ARG D:170 D:169 136.0 0.604 T -90.1 -1.7 136.0 0.604 0.0 WPG
HOH
 5.579
2.222
 NH2
NH1
 OAJ
O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 ARG A:176 A:169 149.0 0.662 T -87.1 1.1 149.0 0.662 0.0 YPG
HOH
 5.795
2.427
 NH1
O
 OAJ
O
ARG B:176 B:169 140.0 0.622 T -79.9 -3.5 140.0 0.622 0.0 YPG
HOH
 5.699
2.720
 NH1
O
 OAJ
O
ARG C:176 C:169 142.0 0.631 T -92.8 -0.3 142.0 0.631 0.0 YPG
HOH
 5.699
2.570
 NH2
O
 OAJ
O
ARG D:176 D:169 143.0 0.636 T -90.2 1.5 143.0 0.636 0.0 YPG
HOH
 5.339
3.652
 NH2
NH2
 OAJ
O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 ARG A:170 A:169 131.0 0.582 T -80.6 -4.9 131.0 0.582 0.0 4X2
HOH
 5.526
2.612
 NH1
O
 O03
O
ARG B:170 B:169 147.0 NA 360.0 75.4 147.0 NA NA HOH
 8.701
 N
 O
ARG C:170 C:169 123.0 0.547 T -101.6 2.1 123.0 0.547 0.0 4X2
HOH
 5.135
2.705
 NH2
NH1
 O01
O
ARG D:170 D:169 61.0 NA T -90.8 26.9 61.0 NA NA 4X2
HOH
 6.293
7.303
 O
C
 O03
O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 ARG A:170 A:169 109.0 0.484 T -85.7 0.4 109.0 0.484 0.0 4X7
HOH
 5.748
3.711
 NH1
NH2
 OAE
O
ARG B:170 B:169 141.0 0.627 T -87.8 6.4 141.0 0.627 0.0 4X7
HOH
 5.777
3.351
 NH1
CD
 OAF
O
ARG C:170 C:169 113.0 0.502 T -79.8 -6.7 113.0 0.502 0.0 4X7
HOH
 5.906
2.795
 NH1
O
 OAE
O
ARG D:170 NA:NA DO NA DO DO DO NA NA NA
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 ARG A:167 A:169 121.0 0.538 T -78.3 -5.6 121.0 0.538 0.0 9YP
HOH
 5.607
2.435
 NH1
NE
 OAD
O
ARG B:167 B:169 52.0 NA -151.2 -167.5 52.0 NA NA 9YP
HOH
 7.002
2.374
 CB
O
 OAH
O
ARG C:167 C:169 136.0 0.604 T -86.8 -4.6 136.0 0.604 0.0 9YP
HOH
 5.224
2.544
 NH2
O
 OAD
O
ARG D:167 D:169 151.0 0.671 T -89.3 15.6 151.0 0.671 0.0 9YP
HOH
 5.473
2.840
 NH2
NE
 OAG
O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 ARG A:166 A:169 117.0 0.52 S -81.2 88.4 117.0 0.52 0.0 PPO
PRP
 7.246
6.467
 NH2
NH2
 N8
O1P
ARG B:166 B:169 107.0 0.476 T -62.7 -24.5 107.0 0.476 0.0 PPO
PRP
HOH
 9.443
6.648
3.494
 CD
CB
CB
 C9
O1P
O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 LEU A:178 A:178 134.0 0.788 T -86.6 27.7 134.0 0.788 0.0 SO4
 8.465
 O
 O4
LEU B:178 B:178 130.0 0.765 T -84.0 0.9 130.0 0.765 0.0 SO4
HOH
 7.497
8.915
 O
CD2
 O2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 ARG A:170 A:170 132.0 0.587 T -81.7 -1.2