Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133632461 . C A CCDS14641.1:NM_000194.2:c.527cCa>cAa_NP_000185.1:p.176P>Q Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 PRO A:175 A:175 16.0 0.11 -67.6 169.6 16.0 0.11 0.0 IMU
HOH
 9.927
4.066
 CG
CD
 O1P
O
PRO B:175 B:175 17.0 0.117 -73.3 170.9 17.0 0.117 0.0 IMU
HOH
 9.720
5.120
 CG
CA
 O1P
O
PRO C:175 C:175 18.0 0.124 -74.0 168.9 18.0 0.124 0.0 IMU
HOH
 9.828
4.752
 CG
O
 O1P
O
PRO D:175 D:175 14.0 0.097 -67.8 170.7 14.0 0.097 0.0 IMU
HOH
 9.787
4.787
 CD
O
 O2P
O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 PRO A:175 A:175 12.0 0.083 -53.4 -178.5 12.0 0.083 0.0 5GP
HOH
 9.279
8.375
 CD
CD
 O2P
O
PRO B:175 B:175 15.0 0.103 -59.4 162.6 15.0 0.103 0.0 5GP
HOH
 9.675
4.478
 CD
C
 O3P
O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 PRO A:175 A:175 12.0 0.083 -62.9 156.7 12.0 0.083 0.0 HOH
 2.634
 O
 O
PRO B:175 B:175 18.0 0.124 -62.6 155.9 18.0 0.124 0.0 HOH
 2.890
 O
 O
PRO C:175 C:175 11.0 0.076 -61.3 156.3 NA NA NA
PRO D:175 D:175 16.0 0.11 -64.2 157.0 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 PRO A:175 A:175 14.0 0.097 -66.2 155.4 14.0 0.097 0.0 24H
HOH
 9.209
2.575
 CG
O
 OAE
O
PRO B:175 B:175 27.0 0.186 -64.6 140.9 27.0 0.186 0.0 24H
HOH
 8.936
3.867
 CG
O
 OAC
O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 PRO A:175 A:175 11.0 0.076 -63.8 161.6 11.0 0.076 0.0 H26
HOH
 9.140
4.868
 CD
CA
 OAC
O
PRO B:175 B:175 25.0 0.172 -65.3 145.4 25.0 0.172 0.0 H26
HOH
 9.697
3.546
 CD
O
 OAC
O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 PRO A:175 A:175 12.0 0.083 -64.5 163.4 12.0 0.083 0.0 25H
HOH
 8.989
3.050
 CD
O
 OAC
O
PRO B:175 B:175 31.0 0.214 -64.6 153.9 31.0 0.214 0.0 25H
HOH
 9.613
3.940
 CD
O
 OAC
O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:175 A:175 16.0 0.11 -73.4 168.9 16.0 0.11 0.0 3L3
HOH
 8.955
3.069
 CD
O
 OAE
O
PRO B:175 B:175 17.0 0.117 -70.2 161.9 17.0 0.117 0.0 3L3
HOH
 9.040
8.198
 CD
CB
 OAC
O
PRO C:175 C:175 11.0 0.076 -69.0 169.8 11.0 0.076 0.0 3L3
HOH
 9.131
6.333
 CG
O
 OAF
O
PRO D:175 D:175 13.0 0.09 -73.9 168.4 13.0 0.09 0.0 3L3
HOH
 8.781
3.561
 CD
C
 OAF
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:175 A:175 16.0 0.11 -68.4 160.3 16.0 0.11 0.0 HOH
 6.057
 O
 O
PRO B:175 B:175 16.0 0.11 -71.6 162.8 16.0 0.11 0.0 3L4
HOH
 9.591
5.982
 CG
O
 OAC
O
PRO C:175 C:175 11.0 0.076 -71.7 156.6 11.0 0.076 0.0 3L4
HOH
 9.274
2.298
 CG
O
 OAE
O
PRO D:175 D:175 11.0 0.076 -72.2 166.6 11.0 0.076 0.0 3L4
HOH
 9.401
6.540
 CD
CD
 OAF
O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:175 A:175 27.0 0.186 -62.6 145.6 27.0 0.186 0.0 3L5
MG
HOH
 8.359
8.594
3.161
 HD3
HB3
HD2
 OAD
MG
O
PRO B:175 B:175 14.0 0.097 -57.4 144.7 14.0 0.097 0.0 3L5
MG
HOH
 8.042
8.112
2.870
 HG3
HG3
HD2
 OAH
MG
O
PRO C:175 C:175 12.0 0.083 -70.4 164.5 12.0 0.083 0.0 3L5
HOH
 7.844
2.808
 HD3
O
 OAH
O
PRO D:175 D:175 13.0 0.09 -68.7 164.9 13.0 0.09 0.0 3L5
HOH
 7.936
2.901
 HD3
O
 OAH
O
PRO E:175 E:175 26.0 0.179 -55.6 136.6 NA NA NA
PRO F:175 F:175 6.0 0.041 -61.0 153.2 NA NA NA
PRO G:175 G:175 17.0 0.117 -57.2 156.3 NA NA NA
PRO H:175 H:175 17.0 0.117 -76.9 169.0 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:175 A:175 13.0 0.09 -73.5 163.9 13.0 0.09 0.0 3L6
HOH
 9.266
5.981
 CD
O
 OAD
O
PRO B:175 B:175 12.0 0.083 -71.1 171.3 12.0 0.083 0.0 3L6
HOH
 9.228
4.350
 CD
CA
 OAF
O
PRO C:175 C:175 15.0 0.103 -69.4 164.8 15.0 0.103 0.0 3L6
 9.215
 CD
 OAD
PRO D:175 D:175 14.0 0.097 -64.0 175.9 14.0 0.097 0.0 3L6
 9.386
 CD
 OAF
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:175 A:175 4.0 0.028 -71.7 171.9 4.0 0.028 0.0 3L7
HOH
 9.073
2.925
 CD
O
 OAC
O
PRO B:175 B:175 21.0 0.145 -64.6 148.8 21.0 0.145 0.0 3L7
HOH
 9.637
2.774
 CD
O
 OAC
O
PRO C:175 C:175 15.0 0.103 -69.1 160.3 15.0 0.103 0.0 3L7
HOH
 9.093
5.891
 CG
O
 OAF
O
PRO D:175 D:175 14.0 0.097 -77.3 168.1 14.0 0.097 0.0 3L7
HOH
 9.225
2.872
 CD
O
 OAC
O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PRO A:175 A:175 15.0 0.103 -69.4 165.2 15.0 0.103 0.0 3L8
HOH
 8.943
4.994
 CG
CA
 OAE
O
PRO B:175 B:175 15.0 0.103 -65.9 152.7 15.0 0.103 0.0 3L8
HOH
 8.971
7.984
 CG
CG
 OAB
O
PRO C:175 C:175 22.0 0.152 -46.4 134.4 22.0 0.152 0.0 3L8
HOH
 9.032
6.192
 CG
CD
 OAE
O
PRO D:175 D:175 13.0 0.09 -78.1 -174.0 13.0 0.09 0.0 3L8
HOH
 9.065
4.191
 CG
CA
 OAD
O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 PRO A:181 A:175 16.0 0.11 -72.2 162.7 16.0 0.11 0.0 SV2
HOH
 9.411
3.628
 CG
CD
 OAD
O
PRO B:181 B:175 13.0 0.09 -73.8 163.7 13.0 0.09 0.0 SV2
HOH
 9.189
2.664
 CG
O
 OAG
O
PRO C:181 C:175 12.0 0.083 -65.9 162.4 12.0 0.083 0.0 SV2
HOH
 8.901
4.378
 CG
CA
 OAD
O
PRO D:181 D:175 13.0 0.09 -68.8 165.2 13.0 0.09 0.0 SV2
HOH
 9.055
6.000
 CD
O
 OAH
O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 PRO A:174 A:175 13.0 0.09 -65.9 164.4 13.0 0.09 0.0 1RP
HOH
 8.525
7.947
 HG3
HG3
 OAH
O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 PRO A:176 A:175 15.0 0.103 -72.4 157.1 15.0 0.103 0.0 WPG
HOH
 9.169
2.775
 CD
O
 OAJ
O
PRO B:176 B:175 14.0 0.097 -74.3 169.3 14.0 0.097 0.0 WPG
HOH
 9.044
2.987
 CD
O
 OAJ
O
PRO C:176 C:175 12.0 0.083 -76.7 172.0 12.0 0.083 0.0 WPG
HOH
 8.743
4.534
 CD
C
 OAJ
O
PRO D:176 D:175 2.0 0.014 -75.2 171.8 2.0 0.014 0.0 WPG
HOH
 9.135
2.727
 CD
O
 OAI
O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 PRO A:182 A:175 12.0 0.083 -71.5 164.3 12.0 0.083 0.0 YPG
HOH
 9.011
2.803
 CD
O
 OAE
O
PRO B:182 B:175 14.0 0.097 -73.5 163.4 14.0 0.097 0.0 YPG
HOH
 9.095
2.718
 CD
O
 OAE
O
PRO C:182 C:175 18.0 0.124 -78.0 169.1 18.0 0.124 0.0 YPG
HOH
 9.046
4.256
 CD
O
 OAE
O
PRO D:182 D:175 13.0 0.09 -76.9 171.2 13.0 0.09 0.0 YPG
HOH
 9.072
4.404
 CD
CA
 OAE
O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 PRO A:176 A:175 14.0 0.097 -75.4 167.2 14.0 0.097 0.0 4X2
HOH
 9.277
4.781
 CD
CD
 O01
O
PRO B:176 B:175 15.0 0.103 -62.8 148.9 15.0 0.103 0.0 4X2
HOH
 9.224
2.413
 CG
O
 O04
O
PRO C:176 C:175 14.0 0.097 -70.7 162.4 14.0 0.097 0.0 4X2
HOH
 9.003
4.487
 CD
CA
 O04
O
PRO D:176 D:175 16.0 0.11 -62.9 166.8 16.0 0.11 0.0 4X2
HOH
 8.896
4.833
 CG
CA
 O01
O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 PRO A:176 A:175 12.0 0.083 -61.6 156.2 12.0 0.083 0.0 4X7
HOH
 8.960
5.939
 CG
O
 OAC
O
PRO B:176 B:175 13.0 0.09 -65.5 160.3 13.0 0.09 0.0 4X7
HOH
 8.990
6.242
 CD
CD
 OAE
O
PRO C:176 C:175 15.0 0.103 -67.6 160.1 15.0 0.103 0.0 4X7
HOH
 9.272
4.380
 CG
C
 OAC
O
PRO D:176 D:175 19.0 0.131 -66.8 164.2 19.0 0.131 0.0 4X7
HOH
 9.390
3.920
 CG
CD
 OAE
O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 PRO A:173 A:175 12.0 0.083 -73.0 166.8 12.0 0.083 0.0 9YP
HOH
 9.312
3.087
 CD
O
 OAH
O
PRO B:173 B:175 14.0 0.097 -72.2 160.7 14.0 0.097 0.0 9YP
HOH
 8.857
4.400
 CG
CA
 OAD
O
PRO C:173 C:175 15.0 0.103 -78.1 158.8 15.0 0.103 0.0 9YP
HOH
 8.781
3.177
 CD
O
 OAH
O
PRO D:173 D:175 10.0 0.069 -70.9 156.6 10.0 0.069 0.0 9YP
HOH
 8.760
2.983
 CD
O
 OAD
O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 PRO A:172 A:175 12.0 0.083 -51.2 157.1 12.0 0.083 0.0 PRP
HOH
 9.444
9.562
 CG
N
 O2P
O
PRO B:172 B:175 7.0 0.048 -66.7 -126.4 7.0 0.048 0.0 PRP
HOH
 9.503
4.917
 CG
N
 O2P
O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 ALA A:184 A:184 19.0 0.165 -69.6 168.6 19.0 0.165 0.0 HOH
 4.693
 CA
 O
ALA B:184 B:184 13.0 0.113 -74.4 161.7 13.0 0.113 0.0 SO4
HOH
 8.508
4.435
 CB
O
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 PRO A:176 A:176 8.0 0.055 -69.4 161.8