Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133632463 . G A CCDS14641.1:NM_000194.2:c.529Gac>Aac_NP_000185.1:p.177D>N Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 ASP A:176 A:176 67.0 0.447 S -79.3 -29.0 67.0 0.447 0.0 HOH
 3.222
 OD1
 O
ASP B:176 B:176 75.0 0.5 S -76.9 -32.6 75.0 0.5 0.0 HOH
 3.147
 OD1
 O
ASP C:176 C:176 71.0 0.473 S -79.2 -29.0 71.0 0.473 0.0 HOH
 3.325
 O
 O
ASP D:176 D:176 74.0 0.493 S -78.2 -33.1 74.0 0.493 0.0 HOH
 2.903
 O
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 ASP A:176 A:176 76.0 0.507 S -92.5 -35.6 76.0 0.507 0.0 HOH
 9.419
 OD2
 O
ASP B:176 B:176 64.0 0.427 S -78.9 -26.2 64.0 0.427 0.0 HOH
 3.321
 OD1
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 ASP A:176 A:176 56.0 0.373 S -74.0 -32.2 56.0 0.373 0.0 HOH
 2.934
 OD1
 O
ASP B:176 B:176 63.0 0.42 S -77.3 -31.2 63.0 0.42 0.0 HOH
 3.994
 O
 O
ASP C:176 C:176 58.0 0.387 S -72.4 -33.6 NA NA NA
ASP D:176 D:176 56.0 0.373 S -77.8 -27.9 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ASP A:176 A:176 76.0 0.507 S -67.3 -36.3 76.0 0.507 0.0 HOH
 3.176
 OD2
 O
ASP B:176 B:176 72.0 0.48 S -78.6 -45.9 72.0 0.48 0.0 HOH
 3.327
 O
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ASP A:176 A:176 77.0 0.513 S -78.2 -25.4 77.0 0.513 0.0 HOH
 3.308
 O
 O
ASP B:176 B:176 68.0 0.453 S -78.6 -40.2 68.0 0.453 0.0 HOH
 3.269
 OD1
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ASP A:176 A:176 79.0 0.527 S -77.1 -26.0 79.0 0.527 0.0 HOH
 3.026
 OD2
 O
ASP B:176 B:176 73.0 0.487 S -84.0 -39.5 73.0 0.487 0.0 HOH
 2.691
 OD2
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:176 A:176 71.0 0.473 S -84.8 -36.3 71.0 0.473 0.0 HOH
 2.741
 OD2
 O
ASP B:176 B:176 70.0 0.467 S -87.6 -23.4 70.0 0.467 0.0
ASP C:176 C:176 67.0 0.447 S -86.0 -29.7 67.0 0.447 0.0 HOH
 3.876
 O
 O
ASP D:176 D:176 71.0 0.473 S -79.8 -32.3 71.0 0.473 0.0 HOH
 2.953
 OD1
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:176 A:176 65.0 0.433 S -76.1 -34.0 65.0 0.433 0.0 HOH
 3.971
 O
 O
ASP B:176 B:176 71.0 0.473 S -74.6 -30.6 71.0 0.473 0.0 HOH
 2.971
 OD1
 O
ASP C:176 C:176 74.0 0.493 S -62.6 -45.0 74.0 0.493 0.0 HOH
 3.776
 O
 O
ASP D:176 D:176 71.0 0.473 S -77.3 -32.4 71.0 0.473 0.0
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:176 A:176 74.0 0.493 S -80.9 -34.1 74.0 0.493 0.0 HOH
 3.036
 OD1
 O
ASP B:176 B:176 36.0 0.24 S -81.3 -32.0 36.0 0.24 0.0 HOH
 3.334
 OD1
 O
ASP C:176 C:176 63.0 0.42 S -85.8 -30.7 63.0 0.42 0.0 HOH
 2.774
 OD2
 O
ASP D:176 D:176 70.0 0.467 S -80.8 -28.9 70.0 0.467 0.0 HOH
 2.291
 OD1
 O
ASP E:176 E:176 52.0 0.347 S -78.1 -28.8 NA NA NA
ASP F:176 F:176 70.0 0.467 S -72.7 -33.2 NA NA NA
ASP G:176 G:176 79.0 0.527 S -81.7 -26.9 NA NA NA
ASP H:176 H:176 59.0 0.393 S -85.0 -31.3 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:176 A:176 75.0 0.5 S -74.0 -25.1 75.0 0.5 0.0 HOH
 3.766
 O
 O
ASP B:176 B:176 61.0 0.407 S -82.0 -29.6 61.0 0.407 0.0 HOH
 3.030
 OD1
 O
ASP C:176 C:176 72.0 0.48 S -80.0 -27.0 72.0 0.48 0.0
ASP D:176 D:176 72.0 0.48 S -82.4 -27.7 72.0 0.48 0.0
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:176 A:176 34.0 0.227 S -87.8 -33.3 34.0 0.227 0.0 HOH
 3.223
 OD2
 O
ASP B:176 B:176 48.0 0.32 S -78.1 -31.7 48.0 0.32 0.0 HOH
 3.866
 O
 O
ASP C:176 C:176 68.0 0.453 S -73.8 -38.5 68.0 0.453 0.0 HOH
 3.751
 O
 O
ASP D:176 D:176 68.0 0.453 S -80.0 -32.6 68.0 0.453 0.0 HOH
 2.831
 OD2
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:176 A:176 71.0 0.473 S -79.8 -22.5 71.0 0.473 0.0 HOH
 3.102
 O
 O
ASP B:176 B:176 66.0 0.44 S -69.9 -39.6 66.0 0.44 0.0 HOH
 8.134
 O
 O
ASP C:176 C:176 45.0 0.3 S -70.7 -39.6 45.0 0.3 0.0 HOH
 7.802
 O
 O
ASP D:176 D:176 51.0 0.34 S -109.3 -28.5 51.0 0.34 0.0 HOH
 3.082
 OD2
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 ASP A:182 A:176 71.0 0.473 S -74.2 -31.9 71.0 0.473 0.0 HOH
 2.736
 OD2
 O
ASP B:182 B:176 71.0 0.473 S -73.7 -30.9 71.0 0.473 0.0 HOH
 2.989
 OD2
 O
ASP C:182 C:176 80.0 0.533 S -71.2 -42.5 80.0 0.533 0.0 HOH
 2.712
 OD2
 O
ASP D:182 D:176 68.0 0.453 S -77.0 -35.6 68.0 0.453 0.0 HOH
 3.034
 OD1
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 ASP A:175 A:176 85.0 0.567 S -79.8 -30.2 85.0 0.567 0.0 HOH
 7.580
 O
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 ASP A:177 A:176 48.0 0.32 S -67.0 -33.6 48.0 0.32 0.0 HOH
 2.503
 OD1
 O
ASP B:177 B:176 60.0 0.4 S -80.0 -30.2 60.0 0.4 0.0 HOH
 2.404
 OD1
 O
ASP C:177 C:176 75.0 0.5 S -79.9 -31.9 75.0 0.5 0.0 HOH
 2.691
 OD2
 O
ASP D:177 D:176 29.0 0.193 S -81.3 -35.9 29.0 0.193 0.0 HOH
 3.011
 OD1
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 ASP A:183 A:176 40.0 0.267 S -76.5 -33.2 40.0 0.267 0.0 HOH
 2.776
 OD2
 O
ASP B:183 B:176 37.0 0.247 S -77.5 -36.1 37.0 0.247 0.0 HOH
 2.422
 OD2
 O
ASP C:183 C:176 72.0 0.48 S -78.7 -31.9 72.0 0.48 0.0 HOH
 2.737
 OD2
 O
ASP D:183 D:176 71.0 0.473 S -83.8 -29.5 71.0 0.473 0.0 HOH
 2.687
 OD2
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 ASP A:177 A:176 73.0 0.487 S -79.4 -34.1 73.0 0.487 0.0 HOH
 3.563
 OD2
 O
ASP B:177 B:176 69.0 0.46 S -69.7 -32.3 69.0 0.46 0.0 HOH
 2.693
 OD1
 O
ASP C:177 C:176 74.0 0.493 S -77.6 -26.1 74.0 0.493 0.0 HOH
 2.447
 OD2
 O
ASP D:177 D:176 67.0 0.447 S -83.4 -30.8 67.0 0.447 0.0 HOH
 2.623
 OD2
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 ASP A:177 A:176 86.0 0.573 S -71.3 -31.8 86.0 0.573 0.0 HOH
 3.982
 O
 O
ASP B:177 B:176 71.0 0.473 S -70.8 -33.3 71.0 0.473 0.0 HOH
 7.369
 O
 O
ASP C:177 C:176 77.0 0.513 S -71.0 -33.3 77.0 0.513 0.0 HOH
 2.766
 OD1
 O
ASP D:177 D:176 70.0 0.467 S -78.7 -38.1 70.0 0.467 0.0 HOH
 3.154
 O
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 ASP A:174 A:176 65.0 0.433 S -79.8 -35.4 65.0 0.433 0.0 HOH
 2.478
 OD1
 O
ASP B:174 B:176 76.0 0.507 S -73.6 -30.7 76.0 0.507 0.0 HOH
 2.424
 OD1
 O
ASP C:174 C:176 72.0 0.48 S -73.3 -25.1 72.0 0.48 0.0 HOH
 2.252
 OD2
 O
ASP D:174 D:176 71.0 0.473 S -71.1 -30.5 71.0 0.473 0.0 HOH
 2.593
 OD1
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 ASP A:173 A:176 56.0 0.373 S -79.8 -20.0 56.0 0.373 0.0 HOH
 6.198
 OD2
 O
ASP B:173 B:176 101.0 0.673 S -163.9 5.4 101.0 0.673 0.0 HOH
 6.692
 OD1
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 ASP A:185 A:185 75.0 0.5 S -84.1 -53.0 75.0 0.5 0.0 HOH
 2.765
 OD2
 O
ASP B:185 B:185 58.0 0.387 S -84.1 -47.9 58.0 0.387 0.0 HOH
 2.820
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 ASP A:177 A:177 28.0 0.187 S -73.7 -33.9