Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 133632644 | . | G | A | CCDS14641.1:NM_000194.2:c.539gGa>gAa_NP_000185.1:p.180G>E | Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1bzy | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
1999-06-22 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -76.8 | -62.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.478 |
N |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -74.9 | -62.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.405 |
N |
O |
|||||||||
| GLY | C:179 | C:179 | 0.0 | 0.0 | E | -80.5 | -58.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.446 |
N |
O |
|||||||||
| GLY | D:179 | D:179 | 0.0 | 0.0 | E | -77.0 | -62.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.224 |
N |
O |
|||||||||
| 1hmp | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
1995-06-03 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -75.4 | -53.4 | 0.0 | 0.0 | 0.0 | ||||||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -83.7 | -52.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.575 |
N |
O |
|||||||||
| 1z7g | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2005-08-02 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -75.1 | -64.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.332 |
N |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -72.6 | -66.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.253 |
N |
O |
|||||||||
| GLY | C:179 | C:179 | 0.0 | 0.0 | E | -71.2 | -66.3 | NA | NA | NA | |||||||||||||
| GLY | D:179 | D:179 | 0.0 | 0.0 | E | -71.0 | -62.3 | NA | NA | NA | |||||||||||||
| 3gep | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2009-08-18 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -68.9 | -64.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.249 |
N |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -67.5 | -65.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.634 |
N |
O |
|||||||||
| 3ggc | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2009-08-18 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -67.4 | -63.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.642 |
N |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -73.3 | -57.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.841 |
N |
O |
|||||||||
| 3ggj | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2009-08-18 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -69.0 | -63.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.624 |
N |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -62.9 | -65.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.244 |
N |
O |
|||||||||
| 4rab | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -70.0 | -66.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.296 |
N |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -75.5 | -61.6 | 0.0 | 0.0 | 0.0 |
HOH |
7.849 |
O |
O |
|||||||||
| GLY | C:179 | C:179 | 0.0 | 0.0 | E | -72.8 | -65.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.487 |
N |
O |
|||||||||
| GLY | D:179 | D:179 | 0.0 | 0.0 | E | -75.8 | -63.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.573 |
N |
O |
|||||||||
| 4rac | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -74.8 | -66.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.483 |
N |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -72.8 | -63.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.471 |
N |
O |
|||||||||
| GLY | C:179 | C:179 | 0.0 | 0.0 | E | -72.7 | -64.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.179 |
N |
O |
|||||||||
| GLY | D:179 | D:179 | 0.0 | 0.0 | E | -68.1 | -66.1 | 0.0 | 0.0 | 0.0 |
HOH |
7.763 |
O |
O |
|||||||||
| 4rad | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -70.7 | -66.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.596 |
N |
O |
||
| GLY | B:179 | B:179 | 1.0 | 0.013 | E | -72.1 | -60.3 | 1.0 | 0.013 | 0.0 |
HOH |
5.557 |
N |
O |
|||||||||
| GLY | C:179 | C:179 | 0.0 | 0.0 | E | -71.4 | -65.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.791 |
O |
O |
|||||||||
| GLY | D:179 | D:179 | 0.0 | 0.0 | E | -74.4 | -65.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.395 |
N |
O |
|||||||||
| GLY | E:179 | E:179 | 0.0 | 0.0 | E | -72.2 | -64.1 | NA | NA | NA | |||||||||||||
| GLY | F:179 | F:179 | 0.0 | 0.0 | E | -70.8 | -67.5 | NA | NA | NA | |||||||||||||
| GLY | G:179 | G:179 | 0.0 | 0.0 | E | -71.9 | -62.6 | NA | NA | NA | |||||||||||||
| GLY | H:179 | H:179 | 0.0 | 0.0 | E | -72.8 | -64.7 | NA | NA | NA | |||||||||||||
| 4ran | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -81.5 | -58.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.621 |
N |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -78.4 | -59.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.199 |
N |
O |
|||||||||
| GLY | C:179 | C:179 | 0.0 | 0.0 | E | -78.3 | -58.7 | 0.0 | 0.0 | 0.0 | |||||||||||||
| GLY | D:179 | D:179 | 0.0 | 0.0 | E | -75.6 | -60.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 4rao | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -71.8 | -62.5 | 0.0 | 0.0 | 0.0 |
HOH |
7.483 |
O |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -70.1 | -66.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.385 |
N |
O |
|||||||||
| GLY | C:179 | C:179 | 0.0 | 0.0 | E | -70.0 | -64.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.370 |
N |
O |
|||||||||
| GLY | D:179 | D:179 | 0.0 | 0.0 | E | -72.2 | -64.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.439 |
N |
O |
|||||||||
| 4raq | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:179 | A:179 | 0.0 | 0.0 | E | -85.0 | -60.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.164 |
N |
O |
||
| GLY | B:179 | B:179 | 0.0 | 0.0 | E | -62.4 | -72.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.532 |
O |
O |
|||||||||
| GLY | C:179 | C:179 | 0.0 | 0.0 | E | -59.4 | -70.6 | 0.0 | 0.0 | 0.0 |
HOH |
7.581 |
O |
O |
|||||||||
| GLY | D:179 | D:179 | 0.0 | 0.0 | E | -69.8 | -62.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.391 |
O |
O |
|||||||||
| 4ijq | 1 | P00492 | 100.0 | 4e-161 |
X-RAY |
2013-03-27 | GLY | A:185 | A:179 | 0.0 | 0.0 | E | -76.9 | -63.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.428 |
N |
O |
||
| GLY | B:185 | B:179 | 0.0 | 0.0 | E | -74.7 | -61.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.455 |
N |
O |
|||||||||
| GLY | C:185 | C:179 | 0.0 | 0.0 | E | -71.3 | -63.6 | 0.0 | 0.0 | 0.0 |
HOH |
7.476 |
O |
O |
|||||||||
| GLY | D:185 | D:179 | 0.0 | 0.0 | E | -70.0 | -66.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.530 |
N |
O |
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| 4kn6 | 1 | P00492 | 100.0 | 1e-160 |
X-RAY |
2013-08-14 | GLY | A:178 | A:179 | 0.0 | 0.0 | E | -78.6 | -60.0 | 0.0 | 0.0 | 0.0 | ||||||
| 6bnj | 1 | P00492 | 99.08 | 6e-160 |
X-RAY |
2017-12-06 | GLY | A:180 | A:179 | 0.0 | 0.0 | E | -76.3 | -61.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.256 |
N |
O |
||
| GLY | B:180 | B:179 | 0.0 | 0.0 | E | -70.7 | -64.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.206 |
N |
O |
|||||||||
| GLY | C:180 | C:179 | 0.0 | 0.0 | E | -73.4 | -62.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.477 |
N |
O |
|||||||||
| GLY | D:180 | D:179 | 0.0 | 0.0 | E | -68.7 | -65.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.271 |
N |
O |
|||||||||
| 5hia | 1 | P00492 | 99.08 | 8e-160 |
X-RAY |
2017-01-18 | GLY | A:186 | A:179 | 0.0 | 0.0 | E | -73.2 | -61.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.241 |
N |
O |
||
| GLY | B:186 | B:179 | 0.0 | 0.0 | E | -73.3 | -64.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.484 |
N |
O |
|||||||||
| GLY | C:186 | C:179 | 0.0 | 0.0 | E | -71.5 | -61.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.353 |
N |
O |
|||||||||
| GLY | D:186 | D:179 | 0.0 | 0.0 | E | -71.8 | -66.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.455 |
N |
O |
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| 5brn | 1 | P00492 | 98.62 | 3e-159 |
X-RAY |
2015-10-14 | GLY | A:180 | A:179 | 0.0 | 0.0 | E | -77.9 | -69.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.364 |
N |
O |
||
| GLY | B:180 | B:179 | 0.0 | 0.0 | E | -78.3 | -66.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.535 |
N |
O |
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| GLY | C:180 | C:179 | 0.0 | 0.0 | E | -77.2 | -67.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.460 |
N |
O |
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| GLY | D:180 | D:179 | 0.0 | 0.0 | E | -75.7 | -63.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.462 |
N |
O |
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| 5bsk | 1 | P00492 | 98.62 | 3e-159 |
X-RAY |
2015-09-23 | GLY | A:180 | A:179 | 0.0 | 0.0 | E | -79.0 | -57.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.344 |
N |
O |
||
| GLY | B:180 | B:179 | 0.0 | 0.0 | E | -82.2 | -59.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.987 |
O |
O |
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| GLY | C:180 | C:179 | 0.0 | 0.0 | E | -77.9 | -61.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.701 |
N |
O |
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| GLY | D:180 | D:179 | 0.0 | 0.0 | E | -75.0 | -62.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.143 |
N |
O |
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| 5w8v | 1 | P00492 | 100.0 | 7e-159 |
X-RAY |
2017-08-30 | GLY | A:177 | A:179 | 0.0 | 0.0 | E | -74.0 | -69.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.967 |
N |
O |
||
| GLY | B:177 | B:179 | 0.0 | 0.0 | E | -78.0 | -66.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.372 |
N |
O |
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| GLY | C:177 | C:179 | 0.0 | 0.0 | E | -75.8 | -59.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.563 |
N |
O |
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| GLY | D:177 | D:179 | 0.0 | 0.0 | E | -76.5 | -63.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.328 |
N |
O |
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| 1d6n | 1 | P00492 | 99.07 | 6e-157 |
X-RAY |
1999-12-30 | GLY | A:176 | A:179 | 0.0 | 0.0 | E | -98.0 | -57.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.095 |
O |
O |
||
| GLY | B:176 | B:179 | 0.0 | 0.0 | E | -64.6 | -75.8 | 0.0 | 0.0 | 0.0 |
HOH |
8.703 |
O |
O |
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| 2vfa | 1 | P20035,P00492 | 80.48 | 3e-122 |
X-RAY |
2008-06-17 | GLY | A:188 | A:188 | 0.0 | 0.0 | E | -70.6 | -62.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.173 |
N |
O |
||
| GLY | B:188 | B:188 | 0.0 | 0.0 | E | -72.4 | -60.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.464 |
N |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00492-f1 | 1 | P00492 | 100.0 | 2e-162 | GLY | A:180 | A:180 | 0.0 | 0.0 | E | -68.2 | -69.0 | |