wupsivus

Variant

Genome	Chromosome	Position	VCF ID	Ref	Alt	mRNA Change	mRNA Info
GRCh37	chrX	133632671	.	T	A	CCDS14641.1:NM_000194.2:c.566gTa>gAa_NP_000185.1:p.189V>E	Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.

pdb_id	:
label_asym_id	:
label_seq_id	:
label_comp_id	:
auth_asym_id	:
auth_seq_id	:

alphafold_id	:
label_asym_id	:
label_seq_id	:
label_comp_id	:
auth_asym_id	:
auth_seq_id	:

PDB

Entity							Residue			Monomer					BioUnit				Ligand				View
PDB	Entity	Uniprot	Identity	Evalue	ExpMethod	Date	Name	Label	Auth	ASA	rASA	SS	φ	ψ	ASA	rASA	ΔASA	Interaction	Name	Distance	Atom(p)	Atom(l)	View
1bzy	1	P00492	100.0	3e-161	X-RAY	1999-06-22	VAL	A:188	A:188	0.0	0.0	E	-137.1	168.1	0.0	0.0	0.0		MG IMU POP HOH	8.178 4.231 9.508 5.488	CG1 CA CG1 N	MG N2 O3 O
							VAL	B:188	B:188	0.0	0.0	E	-137.5	169.0	0.0	0.0	0.0		MG IMU POP HOH	8.244 4.209 9.496 6.958	CG1 CA CG1 CG1	MG N2 O3 O
							VAL	C:188	C:188	0.0	0.0	E	-133.5	170.3	0.0	0.0	0.0		MG IMU POP HOH	8.465 4.331 9.809 7.002	CG1 CA CG1 CG1	MG N2 O3 O
							VAL	D:188	D:188	0.0	0.0	E	-141.4	165.4	0.0	0.0	0.0		MG IMU POP HOH	7.923 4.104 9.346 6.723	CG1 CG1 CG1 CG1	MG N2 O3 O
1hmp	1	P00492	100.0	3e-161	X-RAY	1995-06-03	VAL	A:188	A:188	0.0	0.0	E	-147.3	160.3	0.0	0.0	0.0		5GP HOH	4.283 8.916	CG1 C	N2 O
1hmp	1	P00492	100.0	3e-161	X-RAY	1995-06-03	VAL	B:188	B:188	0.0	0.0	E	-139.8	169.2	0.0	0.0	0.0		5GP HOH	4.718 8.168	CG1 CG1	N2 O
1z7g	1	P00492	100.0	3e-161	X-RAY	2005-08-02	VAL	A:188	A:188	2.0	0.013	E	-140.4	162.5	2.0	0.013	0.0		HOH	4.807	C	O
							VAL	B:188	B:188	1.0	0.006	E	-139.4	168.7	1.0	0.006	0.0		HOH	4.361	C	O
							VAL	C:188	C:188	1.0	0.006	E	-140.0	169.5	NA	NA	NA
							VAL	D:188	D:188	2.0	0.013	E	-137.2	169.0	NA	NA	NA
3gep	1	P00492	100.0	3e-161	X-RAY	2009-08-18	VAL	A:188	A:188	0.0	0.0	E	-136.2	168.4	0.0	0.0	0.0		24H HOH	4.757 5.208	CG1 C	N2 O
3gep	1	P00492	100.0	3e-161	X-RAY	2009-08-18	VAL	B:188	B:188	1.0	0.006	E	-139.8	166.4	1.0	0.006	0.0		24H HOH	4.550 5.378	CG1 C	N2 O
3ggc	1	P00492	100.0	3e-161	X-RAY	2009-08-18	VAL	A:188	A:188	1.0	0.006	E	-132.9	163.4	1.0	0.006	0.0		H26 HOH	5.054 5.019	N C	N1 O
3ggc	1	P00492	100.0	3e-161	X-RAY	2009-08-18	VAL	B:188	B:188	0.0	0.0	E	-128.9	167.9	0.0	0.0	0.0		H26 HOH	4.968 7.784	N CG1	N1 O
3ggj	1	P00492	100.0	3e-161	X-RAY	2009-08-18	VAL	A:188	A:188	0.0	0.0	E	-138.0	166.6	0.0	0.0	0.0		25H HOH	4.728 5.238	CG1 C	N2 O
3ggj	1	P00492	100.0	3e-161	X-RAY	2009-08-18	VAL	B:188	B:188	0.0	0.0	E	-139.8	171.5	0.0	0.0	0.0		25H HOH	4.181 7.460	CG1 CG1	N2 O
4rab	1	P00492	100.0	3e-161	X-RAY	2015-01-07	VAL	A:188	A:188	0.0	0.0	E	-131.9	169.2	0.0	0.0	0.0		3L3 HOH	4.510 8.673	CG1 CB	N2 O
							VAL	B:188	B:188	0.0	0.0	E	-135.4	170.4	0.0	0.0	0.0		3L3 PO4 HOH	4.400 9.735 8.716	CG1 CG1 CB	N2 O1 O
							VAL	C:188	C:188	0.0	0.0	E	-138.1	170.6	0.0	0.0	0.0		3L3 MG PO4 HOH	4.282 8.876 9.736 7.701	CG1 CG1 CG1 CA	N2 MG O3 O
							VAL	D:188	D:188	0.0	0.0	B	-133.8	169.9	0.0	0.0	0.0		3L3 MG PO4 HOH	4.368 8.048 9.834 8.725	CG1 CG1 CG1 CB	N2 MG O4 O
4rac	1	P00492	100.0	3e-161	X-RAY	2015-01-07	VAL	A:188	A:188	0.0	0.0	B	-142.3	167.5	0.0	0.0	0.0		3L4 MG HOH	4.544 8.458 6.956	CG1 CG1 CG1	N2 MG O
							VAL	B:188	B:188	0.0	0.0	E	-140.3	163.6	0.0	0.0	0.0		3L4 MG HOH	4.614 8.191 6.602	CG1 CG1 CG1	N2 MG O
							VAL	C:188	C:188	0.0	0.0	E	-134.5	172.0	0.0	0.0	0.0		3L4 MG HOH	4.549 8.476 6.872	CG1 CG1 CG1	N2 MG O
							VAL	D:188	D:188	0.0	0.0	B	-127.7	168.4	0.0	0.0	0.0		3L4 HOH	4.948 7.701	CG1 CA	N2 O
4rad	1	P00492	100.0	3e-161	X-RAY	2015-01-07	VAL	A:188	A:188	0.0	0.0	E	-136.7	169.2	0.0	0.0	0.0		3L5 HOH	3.327 5.881	HG12 HG12	H24 O
							VAL	B:188	B:188	0.0	0.0	E	-136.1	162.1	0.0	0.0	0.0		3L5 MG HOH	3.016 7.493 5.585	HG12 HG12 HG12	H24 MG O
							VAL	C:188	C:188	0.0	0.0	E	-135.0	166.5	0.0	0.0	0.0		3L5 HOH	3.130 6.344	HG12 HG12	H23 O
							VAL	D:188	D:188	0.0	0.0	B	-139.4	167.7	0.0	0.0	0.0		3L5 HOH	3.015 4.369	HG12 HG13	H23 O
							VAL	E:188	E:188	0.0	0.0	E	-134.7	173.6	NA	NA	NA
							VAL	F:188	F:188	0.0	0.0	E	-136.4	167.2	NA	NA	NA
							VAL	G:188	G:188	0.0	0.0	E	-132.2	168.7	NA	NA	NA
							VAL	H:188	H:188	0.0	0.0	E	-136.5	166.4	NA	NA	NA
4ran	1	P00492	100.0	3e-161	X-RAY	2015-01-07	VAL	A:188	A:188	0.0	0.0	E	-136.7	176.1	0.0	0.0	0.0		3L6 HOH	4.739 8.286	CG1 CG1	N2 O
							VAL	B:188	B:188	0.0	0.0	E	-137.0	169.3	0.0	0.0	0.0		3L6	4.951	CG1	N2
							VAL	C:188	C:188	0.0	0.0	E	-139.7	169.6	0.0	0.0	0.0		3L6 HOH	4.979 9.263	CG1 CA	N2 O
							VAL	D:188	D:188	0.0	0.0	E	-132.1	175.4	0.0	0.0	0.0		3L6 HOH	4.888 9.915	CG1 O	N2 O
4rao	1	P00492	100.0	3e-161	X-RAY	2015-01-07	VAL	A:188	A:188	0.0	0.0	E	-138.3	171.5	0.0	0.0	0.0		3L7 MG HOH	4.949 8.346 6.473	N CG1 CG1	N1 MG O
							VAL	B:188	B:188	0.0	0.0	E	-140.3	167.5	0.0	0.0	0.0		3L7 MG HOH	4.840 8.288 6.465	N CG1 CG1	N1 MG O
							VAL	C:188	C:188	0.0	0.0	E	-139.6	168.4	0.0	0.0	0.0		3L7 MG HOH	4.902 8.299 6.667	N CG1 CG1	N1 MG O
							VAL	D:188	D:188	0.0	0.0	E	-140.8	172.9	0.0	0.0	0.0		3L7 MG HOH	4.862 8.171 6.515	N CG1 CG1	N1 MG O
4raq	1	P00492	100.0	3e-161	X-RAY	2015-01-07	VAL	A:188	A:188	0.0	0.0	E	-139.7	168.2	0.0	0.0	0.0		3L8 MG HOH	4.958 8.716 6.670	N CG1 CG1	N1 MG O
							VAL	B:188	B:188	0.0	0.0	E	-136.6	175.2	0.0	0.0	0.0		3L8 MG HOH	4.936 8.766 6.882	N CG1 CG1	N1 MG O
							VAL	C:188	C:188	0.0	0.0	E	-139.4	162.9	0.0	0.0	0.0		3L8 MG HOH	5.177 8.912 7.076	N CG1 CG1	N1 MG O
							VAL	D:188	D:188	0.0	0.0	E	-131.6	170.2	0.0	0.0	0.0		3L8 MG HOH	4.911 8.409 7.821	N CG1 CG1	N1 MG O
4ijq	1	P00492	100.0	4e-161	X-RAY	2013-03-27	VAL	A:194	A:188	0.0	0.0	E	-136.9	171.2	0.0	0.0	0.0		SV2 SO4 MG HOH	4.882 9.556 8.151 6.853	CG1 CG1 CG1 CG1	N2 O4 MG O
							VAL	B:194	B:188	0.0	0.0	E	-139.2	168.4	0.0	0.0	0.0		SV2 SO4 MG HOH	4.743 9.476 8.201 6.682	CG1 CG1 CG1 CG1	N2 O1 MG O
							VAL	C:194	C:188	1.0	0.006	B	-139.2	170.4	1.0	0.006	0.0		SV2 MG SO4 HOH	4.976 9.305 9.745 5.217	CG1 CG1 CG1 CG1	N2 MG O1 O
							VAL	D:194	D:188	0.0	0.0	E	-137.4	173.0	0.0	0.0	0.0		MG SV2 SO4 HOH	8.087 4.899 9.418 6.696	CG1 CG1 CG1 CG1	MG N2 O4 O
4kn6	1	P00492	100.0	1e-160	X-RAY	2013-08-14	VAL	A:187	A:188	0.0	0.0	E	-137.2	170.3	0.0	0.0	0.0		1RP HOH	4.338 5.432	HG12 C	FAI O
6bnj	1	P00492	99.08	6e-160	X-RAY	2017-12-06	VAL	A:189	A:188	1.0	0.006	B	-133.3	172.1	1.0	0.006	0.0		WPG MG HOH	4.459 8.329 5.382	CG1 CG1 N	N2 MG O
							VAL	B:189	B:188	0.0	0.0	E	-143.2	165.6	0.0	0.0	0.0		WPG MG HOH	4.357 8.163 5.692	CG1 CG1 N	N2 MG O
							VAL	C:189	C:188	0.0	0.0	B	-137.7	172.8	0.0	0.0	0.0		WPG MG HOH	4.427 8.241 5.265	CG1 CG1 N	N2 MG O
							VAL	D:189	D:188	0.0	0.0	E	-139.9	172.1	0.0	0.0	0.0		WPG MG HOH	4.308 8.052 5.307	CG1 CG1 N	N2 MG O
5hia	1	P00492	99.08	8e-160	X-RAY	2017-01-18	VAL	A:195	A:188	0.0	0.0	E	-137.0	169.1	0.0	0.0	0.0		YPG MG HOH	4.365 8.228 6.871	CG1 CG1 CG1	N2 MG O
							VAL	B:195	B:188	0.0	0.0	E	-139.7	167.1	0.0	0.0	0.0		YPG MG HOH	4.501 8.339 7.072	CG1 CG1 CG1	N2 MG O
							VAL	C:195	C:188	0.0	0.0	E	-135.5	168.9	0.0	0.0	0.0		YPG MG HOH	4.543 8.333 7.204	CG1 CG1 CG1	N2 MG O
							VAL	D:195	D:188	0.0	0.0	E	-138.3	170.4	0.0	0.0	0.0		YPG MG HOH	4.433 8.251 6.905	CG1 CG1 CG1	N2 MG O
5brn	1	P00492	98.62	3e-159	X-RAY	2015-10-14	VAL	A:189	A:188	1.0	0.006	B	-132.5	172.1	1.0	0.006	0.0		4X2 HOH	5.008 4.906	N N	N16 O
							VAL	B:189	B:188	0.0	0.0	E	-131.6	166.8	0.0	0.0	0.0		4X2 HOH	5.143 6.999	N CG1	N16 O
							VAL	C:189	C:188	0.0	0.0	E	-139.5	172.1	0.0	0.0	0.0		4X2 HOH	4.995 6.771	N CG1	N16 O
							VAL	D:189	D:188	0.0	0.0	E	-135.3	173.0	0.0	0.0	0.0		4X2 HOH	5.115 8.203	N CA	N16 O
5bsk	1	P00492	98.62	3e-159	X-RAY	2015-09-23	VAL	A:189	A:188	1.0	0.006	E	-136.3	164.2	1.0	0.006	0.0		4X7 HOH	4.517 9.959	CG1 N	N2 O
							VAL	B:189	B:188	0.0	0.0	E	-135.9	163.6	0.0	0.0	0.0		4X7 HOH	4.568 8.198	CG1 C	N2 O
							VAL	C:189	C:188	0.0	0.0	E	-133.6	160.3	0.0	0.0	0.0		4X7 HOH	4.287 9.601	CG1 CB	N2 O
							VAL	D:189	D:188	0.0	0.0	E	-132.5	174.2	0.0	0.0	0.0		4X7 HOH	4.307 8.815	CG1 O	N2 O
5w8v	1	P00492	100.0	7e-159	X-RAY	2017-08-30	VAL	A:186	A:188	0.0	0.0	B	-135.8	-178.4	0.0	0.0	0.0		9YP HOH	4.799 5.315	CG1 N	NAA O
							VAL	B:186	B:188	0.0	0.0	B	-127.7	177.3	0.0	0.0	0.0		9YP HOH	5.051 5.153	CG1 N	NAA O
							VAL	C:186	C:188	0.0	0.0	B	-126.3	175.0	0.0	0.0	0.0		9YP HOH	4.957 5.198	CG1 CG1	NAA O
							VAL	D:186	D:188	0.0	0.0	B	-131.3	171.7	0.0	0.0	0.0		9YP HOH	5.130 5.045	CG1 CG1	NAA O
1d6n	1	P00492	99.07	6e-157	X-RAY	1999-12-30	VAL	A:185	A:188	0.0	0.0		-137.0	139.0	0.0	0.0	0.0		PPO HOH	4.475 9.961	CG1 CG2	N1 O
1d6n	1	P00492	99.07	6e-157	X-RAY	1999-12-30	VAL	B:185	B:188	1.0	0.006		-155.3	-167.3	1.0	0.006	0.0		PPO PRP	4.880 7.003	CG1 CA	O6 O1B
2vfa	1	P20035,P00492	80.48	3e-122	X-RAY	2008-06-17	VAL	A:197	A:197	1.0	0.006	E	-128.1	-179.9	1.0	0.006	0.0		5GP	5.492	N	N1
2vfa	1	P20035,P00492	80.48	3e-122	X-RAY	2008-06-17	VAL	B:197	B:197	1.0	0.006	E	-130.9	163.4	1.0	0.006	0.0		5GP HOH	4.355 9.115	CG1 N	N2 O

AlphaFold DB

Entity					Residue			Monomer					View
ID	Entity	Uniprot	Identity	Evalue	Name	Label	Auth	ASA	rASA	SS	φ	ψ	View
af-p00492-f1	1	P00492	100.0	2e-162	VAL	A:189	A:189	0.0	0.0	E	-135.1	168.2

wupsivus
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