Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133632673 . G A CCDS14641.1:NM_000194.2:c.568Gga>Aga_NP_000185.1:p.190G>R Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 GLY A:189 A:189 0.0 0.0 B 99.2 164.3 0.0 0.0 0.0 MG
IMU
POP
HOH
 9.185
5.556
9.403
5.769
 N
N
O
O
 MG
N2
O3
O
GLY B:189 B:189 0.0 0.0 B 101.3 161.2 0.0 0.0 0.0 MG
IMU
POP
HOH
 9.343
5.541
9.636
5.901
 N
N
O
O
 MG
N2
O3
O
GLY C:189 C:189 0.0 0.0 B 100.3 163.9 0.0 0.0 0.0 MG
IMU
POP
HOH
 9.310
5.583
9.560
5.758
 N
N
O
O
 MG
N2
O3
O
GLY D:189 D:189 0.0 0.0 B 104.5 166.2 0.0 0.0 0.0 MG
IMU
POP
HOH
 9.204
5.536
9.357
5.927
 N
N
O
O
 MG
N2
O3
O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 GLY A:189 A:189 0.0 0.0 B 103.3 159.5 0.0 0.0 0.0 5GP
HOH
 6.141
6.191
 N
C
 N2
O
GLY B:189 B:189 0.0 0.0 B 103.9 163.3 0.0 0.0 0.0 5GP
HOH
 6.709
5.772
 N
C
 N2
O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 GLY A:189 A:189 1.0 0.013 B 109.9 160.8 1.0 0.013 0.0 HOH
 3.332
 C
 O
GLY B:189 B:189 0.0 0.0 B 101.4 161.6 0.0 0.0 0.0 HOH
 3.036
 CA
 O
GLY C:189 C:189 0.0 0.0 B 103.9 158.0 NA NA NA
GLY D:189 D:189 0.0 0.0 B 103.0 157.9 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLY A:189 A:189 0.0 0.0 B 103.5 167.3 0.0 0.0 0.0 24H
HOH
 6.492
3.401
 N
C
 N2
O
GLY B:189 B:189 0.0 0.0 B 100.1 158.8 0.0 0.0 0.0 24H
HOH
 6.422
3.544
 N
C
 N2
O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLY A:189 A:189 2.0 0.027 B 115.8 167.3 2.0 0.027 0.0 H26
HOH
 7.220
3.025
 N
C
 N1
O
GLY B:189 B:189 1.0 0.013 B 103.0 168.6 1.0 0.013 0.0 H26
HOH
 7.206
5.548
 N
C
 N1
O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLY A:189 A:189 0.0 0.0 B 106.8 170.6 0.0 0.0 0.0 25H
HOH
 6.433
3.313
 N
C
 N2
O
GLY B:189 B:189 0.0 0.0 B 98.5 176.3 0.0 0.0 0.0 25H
HOH
 6.308
5.258
 N
C
 N2
O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:189 A:189 0.0 0.0 B 102.5 164.1 0.0 0.0 0.0 3L3
PO4
HOH
 5.868
9.832
6.168
 N
O
O
 N2
O2
O
GLY B:189 B:189 0.0 0.0 B 101.4 164.1 0.0 0.0 0.0 3L3
PO4
HOH
 5.918
9.707
6.205
 N
O
O
 N2
O4
O
GLY C:189 C:189 0.0 0.0 B 102.1 164.8 0.0 0.0 0.0 3L3
PO4
HOH
 5.827
9.929
5.187
 N
O
C
 N2
O3
O
GLY D:189 D:189 0.0 0.0 B 102.4 163.9 0.0 0.0 0.0 3L3
MG
PO4
HOH
 5.822
9.664
9.432
6.029
 N
N
O
O
 N2
MG
O4
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:189 A:189 0.0 0.0 B 95.8 169.8 0.0 0.0 0.0 3L4
MG
HOH
 6.029
9.725
5.916
 N
N
O
 N2
MG
O
GLY B:189 B:189 0.0 0.0 B 107.4 165.5 0.0 0.0 0.0 3L4
MG
HOH
 6.267
9.651
6.003
 N
N
O
 N2
MG
O
GLY C:189 C:189 0.0 0.0 B 95.7 169.3 0.0 0.0 0.0 3L4
MG
HOH
 6.013
9.702
5.925
 N
N
O
 N2
MG
O
GLY D:189 D:189 0.0 0.0 B 103.7 167.2 0.0 0.0 0.0 3L4
HOH
 6.310
6.100
 N
O
 N2
O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:189 A:189 0.0 0.0 B 101.3 167.2 0.0 0.0 0.0 3L5
HOH
 5.424
5.988
 H
O
 H23
O
GLY B:189 B:189 0.0 0.0 B 109.1 165.3 0.0 0.0 0.0 3L5
MG
HOH
 4.852
9.040
5.317
 H
H
C
 H24
MG
O
GLY C:189 C:189 0.0 0.0 B 105.0 163.2 0.0 0.0 0.0 3L5
HOH
 4.982
5.182
 H
C
 H23
O
GLY D:189 D:189 0.0 0.0 B 105.2 167.6 0.0 0.0 0.0 3L5
HOH
 5.344
5.920
 H
O
 H24
O
GLY E:189 E:189 0.0 0.0 B 100.0 163.1 NA NA NA
GLY F:189 F:189 0.0 0.0 B 107.0 164.7 NA NA NA
GLY G:189 G:189 0.0 0.0 B 105.7 162.3 NA NA NA
GLY H:189 H:189 0.0 0.0 B 104.2 166.4 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:189 A:189 0.0 0.0 B 92.3 169.2 0.0 0.0 0.0 3L6
HOH
 6.437
7.670
 N
CA
 N2
O
GLY B:189 B:189 0.0 0.0 B 100.2 165.5 0.0 0.0 0.0 3L6
 6.278
 N
 N2
GLY C:189 C:189 0.0 0.0 B 103.1 167.7 0.0 0.0 0.0 3L6
HOH
 6.374
9.119
 N
O
 N2
O
GLY D:189 D:189 0.0 0.0 B 98.4 163.6 0.0 0.0 0.0 3L6
HOH
 6.447
8.075
 N
CA
 N2
O
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:189 A:189 0.0 0.0 B 100.4 166.7 0.0 0.0 0.0 3L7
MG
HOH
 7.150
9.856
5.881
 N
N
O
 N1
MG
O
GLY B:189 B:189 0.0 0.0 B 105.3 166.7 0.0 0.0 0.0 3L7
MG
HOH
 6.990
9.655
6.087
 N
N
O
 N1
MG
O
GLY C:189 C:189 0.0 0.0 B 102.6 168.8 0.0 0.0 0.0 3L7
MG
HOH
 7.078
9.564
5.955
 N
N
O
 N1
MG
O
GLY D:189 D:189 0.0 0.0 B 100.5 164.9 0.0 0.0 0.0 3L7
MG
HOH
 7.054
9.684
6.076
 N
N
O
 N1
MG
O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:189 A:189 0.0 0.0 B 105.8 165.9 0.0 0.0 0.0 3L8
HOH
 7.071
5.700
 N
O
 N1
O
GLY B:189 B:189 0.0 0.0 B 95.8 168.3 0.0 0.0 0.0 3L8
HOH
 7.109
6.768
 N
O
 N1
O
GLY C:189 C:189 0.0 0.0 B 104.6 174.6 0.0 0.0 0.0 3L8
HOH
 7.010
6.873
 N
O
 N1
O
GLY D:189 D:189 0.0 0.0 B 103.8 167.2 0.0 0.0 0.0 3L8
HOH
 7.131
6.292
 N
O
 N1
O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 GLY A:195 A:189 0.0 0.0 B 98.4 167.2 0.0 0.0 0.0 SV2
SO4
MG
HOH
 6.735
9.427
9.492
5.974
 N
O
N
O
 N2
O1
MG
O
GLY B:195 B:189 0.0 0.0 B 103.2 162.0 0.0 0.0 0.0 SV2
SO4
MG
HOH
 6.566
9.697
9.648
5.967
 N
O
N
O
 N2
O4
MG
O
GLY C:195 C:189 0.0 0.0 B 97.9 168.7 0.0 0.0 0.0 SV2
SO4
HOH
 6.573
9.488
6.001
 N
O
O
 N2
O4
O
GLY D:195 D:189 0.0 0.0 B 100.4 164.9 0.0 0.0 0.0 MG
SV2
SO4
HOH
 9.572
6.668
9.533
5.977
 N
N
O
O
 MG
N2
O4
O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 GLY A:188 A:189 0.0 0.0 B 106.6 173.7 0.0 0.0 0.0 1RP
HOH
 6.158
3.030
 H
HA2
 FAI
O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 GLY A:190 A:189 0.0 0.0 B 99.6 163.4 0.0 0.0 0.0 WPG
MG
HOH
 5.878
9.361
5.614
 N
N
C
 N2
MG
O
GLY B:190 B:189 0.0 0.0 B 105.7 163.7 0.0 0.0 0.0 WPG
MG
HOH
 5.921
9.425
6.054
 N
N
O
 N2
MG
O
GLY C:190 C:189 0.0 0.0 B 103.0 163.2 0.0 0.0 0.0 WPG
MG
HOH
 5.872
9.335
5.270
 N
N
C
 N2
MG
O
GLY D:190 D:189 0.0 0.0 B 99.6 167.6 0.0 0.0 0.0 WPG
MG
HOH
 5.941
9.274
5.876
 N
N
C
 N2
MG
O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 GLY A:196 A:189 0.0 0.0 B 102.7 163.1 0.0 0.0 0.0 YPG
MG
HOH
 5.869
9.427
5.402
 N
N
C
 N2
MG
O
GLY B:196 B:189 0.0 0.0 B 104.2 167.1 0.0 0.0 0.0 YPG
MG
HOH
 6.003
9.486
5.929
 N
N
O
 N2
MG
O
GLY C:196 C:189 0.0 0.0 B 99.9 169.0 0.0 0.0 0.0 YPG
MG
HOH
 5.948
9.283
6.124
 N
N
O
 N2
MG
O
GLY D:196 D:189 0.0 0.0 B 102.6 162.8 0.0 0.0 0.0 YPG
MG
HOH
 5.894
9.398
6.143
 N
N
O
 N2
MG
O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 GLY A:190 A:189 0.0 0.0 B 99.2 167.1 0.0 0.0 0.0 4X2
HOH
 7.013
5.936
 N
O
 N16
O
GLY B:190 B:189 0.0 0.0 B 103.1 168.6 0.0 0.0 0.0 4X2
HOH
 7.022
5.932
 N
O
 N16
O
GLY C:190 C:189 0.0 0.0 B 97.1 166.3 0.0 0.0 0.0 4X2
HOH
 7.017
5.822
 N
O
 N16
O
GLY D:190 D:189 0.0 0.0 B 101.8 162.8 0.0 0.0 0.0 4X2
HOH
 6.996
6.184
 N
O
 N16
O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 GLY A:190 A:189 0.0 0.0 B 111.3 167.4 0.0 0.0 0.0 4X7
HOH
 6.442
8.226
 N
O
 N2
O
GLY B:190 B:189 0.0 0.0 B 109.4 170.2 0.0 0.0 0.0 4X7
HOH
 6.375
5.239
 N
C
 N2
O
GLY C:190 C:189 0.0 0.0 B 117.6 170.2 0.0 0.0 0.0 4X7
HOH
 6.333
9.185
 N
CA
 N2
O
GLY D:190 D:189 0.0 0.0 B 90.0 144.8 0.0 0.0 0.0 4X7
HOH
 6.349
7.348
 N
CA
 N2
O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 GLY A:187 A:189 0.0 0.0 B 87.8 168.0 0.0 0.0 0.0 9YP
HOH
 6.389
6.121
 N
O
 NAA
O
GLY B:187 B:189 0.0 0.0 B 97.1 166.8 0.0 0.0 0.0 9YP
HOH
 6.381
5.012
 N
C
 NAA
O
GLY C:187 C:189 0.0 0.0 B 94.3 164.6 0.0 0.0 0.0 9YP
HOH
 6.385
5.480
 N
C
 NAA
O
GLY D:187 D:189 0.0 0.0 B 98.6 165.5 0.0 0.0 0.0 9YP
HOH
 6.498
5.016
 N
C
 NAA
O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 GLY A:186 A:189 0.0 0.0 S 124.7 130.7 0.0 0.0 0.0 PPO
 7.240
 N
 N1
GLY B:186 B:189 0.0 0.0 S 63.4 142.2 0.0 0.0 0.0 PPO
PRP
HOH
 6.986
6.990
9.086
 N
N
C
 O6
O1B
O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 GLY A:198 A:198 0.0 0.0 S 92.9 179.2 0.0 0.0 0.0 5GP
HOH
 7.638
8.390
 N
C
 N2
O
GLY B:198 B:198 1.0 0.013 B 117.1 171.4 1.0 0.013 0.0 5GP
HOH
 5.881
7.881
 N
CA
 N2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 GLY A:190 A:190 0.0 0.0 B 90.5 168.9