Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133632700 . T A CCDS14641.1:NM_000194.2:c.595Ttc>Atc_NP_000185.1:p.199F>I Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 PHE A:198 A:198 0.0 0.0 S 78.1 4.5 0.0 0.0 0.0 MG
IMU
POP
HOH
 9.342
7.028
9.302
3.578
 CB
CB
C
N
 MG
N2
O3
O
PHE B:198 B:198 0.0 0.0 S 76.4 4.3 0.0 0.0 0.0 MG
IMU
POP
HOH
 9.430
7.027
9.407
3.455
 C
CB
C
N
 MG
N2
O3
O
PHE C:198 C:198 0.0 0.0 S 79.2 11.9 0.0 0.0 0.0 MG
IMU
POP
HOH
 9.274
6.860
9.192
3.442
 C
CB
C
N
 MG
N2
O3
O
PHE D:198 D:198 0.0 0.0 S 78.0 9.1 0.0 0.0 0.0 MG
IMU
POP
HOH
 9.336
6.930
9.419
3.368
 CB
CB
C
N
 MG
N2
O3
O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 PHE A:198 A:198 1.0 0.005 S 74.1 4.2 1.0 0.005 0.0 5GP
HOH
 7.330
3.711
 CD2
N
 N2
O
PHE B:198 B:198 0.0 0.0 S 79.3 16.4 0.0 0.0 0.0 5GP
HOH
 7.585
3.472
 CD2
N
 N2
O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 PHE A:198 A:198 1.0 0.005 S 78.6 8.6 1.0 0.005 0.0 HOH
 2.734
 O
 O
PHE B:198 B:198 0.0 0.0 S 74.9 8.8 0.0 0.0 0.0 HOH
 2.878
 O
 O
PHE C:198 C:198 1.0 0.005 S 76.7 8.9 NA NA NA
PHE D:198 D:198 0.0 0.0 S 75.9 7.3 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 PHE A:198 A:198 1.0 0.005 S 75.0 3.1 1.0 0.005 0.0 24H
HOH
 8.128
2.793
 CD2
O
 N2
O
PHE B:198 B:198 0.0 0.0 S 72.6 4.3 0.0 0.0 0.0 24H
HOH
 7.795
2.971
 CD2
O
 N2
O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 PHE A:198 A:198 1.0 0.005 S 65.0 9.2 1.0 0.005 0.0 H26
HOH
 9.081
2.807
 CD2
O
 C2
O
PHE B:198 B:198 0.0 0.0 S 79.4 3.1 0.0 0.0 0.0 H26
HOH
 8.681
3.128
 CD2
N
 C2
O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 PHE A:198 A:198 1.0 0.005 S 70.8 14.5 1.0 0.005 0.0 25H
HOH
 8.027
2.663
 CD2
O
 N2
O
PHE B:198 B:198 0.0 0.0 S 73.2 4.2 0.0 0.0 0.0 25H
HOH
 7.530
3.221
 CD2
N
 N2
O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PHE A:198 A:198 0.0 0.0 S 75.0 8.0 0.0 0.0 0.0 3L3
PO4
HOH
 7.214
9.826
3.384
 CB
C
N
 N2
O2
O
PHE B:198 B:198 0.0 0.0 S 76.6 2.2 0.0 0.0 0.0 3L3
HOH
 7.344
3.400
 CB
N
 N2
O
PHE C:198 C:198 0.0 0.0 S 73.2 2.4 0.0 0.0 0.0 3L3
MG
PO4
HOH
 7.207
9.990
9.937
3.581
 CB
C
C
N
 N2
MG
O3
O
PHE D:198 D:198 0.0 0.0 S 74.4 5.9 0.0 0.0 0.0 3L3
MG
PO4
HOH
 7.167
9.492
9.615
3.497
 CB
CD2
C
N
 N2
MG
O4
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PHE A:198 A:198 0.0 0.0 T 79.9 2.3 0.0 0.0 0.0 3L4
MG
HOH
 7.362
9.797
3.380
 CB
CB
N
 N2
MG
O
PHE B:198 B:198 0.0 0.0 S 71.7 5.6 0.0 0.0 0.0 3L4
MG
HOH
 7.583
9.662
3.361
 CB
CB
N
 N2
MG
O
PHE C:198 C:198 0.0 0.0 S 73.1 0.9 0.0 0.0 0.0 3L4
MG
HOH
 7.411
9.871
3.484
 CB
CB
N
 N2
MG
O
PHE D:198 D:198 0.0 0.0 S 81.4 -1.0 0.0 0.0 0.0 3L4
HOH
 7.768
3.395
 CB
N
 N2
O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PHE A:198 A:198 0.0 0.0 S 72.7 0.8 0.0 0.0 0.0 3L5
HOH
 6.311
3.212
 HB2
H
 H24
O
PHE B:198 B:198 0.0 0.0 S 76.5 -1.8 0.0 0.0 0.0 3L5
MG
HOH
 6.028
9.007
3.193
 HB2
HB2
H
 H24
MG
O
PHE C:198 C:198 0.0 0.0 S 72.1 -3.0 0.0 0.0 0.0 3L5
HOH
 6.261
3.266
 HB2
H
 H23
O
PHE D:198 D:198 0.0 0.0 S 71.5 3.2 0.0 0.0 0.0 3L5
HOH
 6.220
3.362
 HB2
H
 H23
O
PHE E:198 E:198 0.0 0.0 S 74.4 7.5 NA NA NA
PHE F:198 F:198 0.0 0.0 S 77.0 4.3 NA NA NA
PHE G:198 G:198 0.0 0.0 S 74.1 2.8 NA NA NA
PHE H:198 H:198 0.0 0.0 S 72.4 2.9 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PHE A:198 A:198 0.0 0.0 S 72.9 2.2 0.0 0.0 0.0 3L6
HOH
 7.826
7.442
 CB
O
 N2
O
PHE B:198 B:198 0.0 0.0 S 75.3 5.5 0.0 0.0 0.0 3L6
 7.858
 CB
 N2
PHE C:198 C:198 0.0 0.0 S 74.6 1.8 0.0 0.0 0.0 3L6
 7.746
 CB
 N2
PHE D:198 D:198 0.0 0.0 S 67.8 12.5 0.0 0.0 0.0 3L6
HOH
 7.720
8.055
 CB
O
 N2
O
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PHE A:198 A:198 0.0 0.0 S 75.8 7.1 0.0 0.0 0.0 3L7
MG
HOH
 8.792
9.783
3.356
 CB
C
N
 C2
MG
O
PHE B:198 B:198 0.0 0.0 T 77.2 4.5 0.0 0.0 0.0 3L7
MG
HOH
 8.523
9.650
3.463
 CB
CB
N
 C2
MG
O
PHE C:198 C:198 0.0 0.0 S 77.7 -0.3 0.0 0.0 0.0 3L7
MG
HOH
 8.798
9.771
6.199
 CB
CB
O
 C2
MG
O
PHE D:198 D:198 0.0 0.0 S 76.1 5.5 0.0 0.0 0.0 3L7
MG
HOH
 8.675
9.665
3.428
 CB
CB
N
 C2
MG
O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 PHE A:198 A:198 0.0 0.0 S 71.5 11.0 0.0 0.0 0.0 3L8
HOH
 8.554
3.211
 CD2
N
 C2
O
PHE B:198 B:198 0.0 0.0 S 80.1 2.8 0.0 0.0 0.0 3L8
HOH
 8.663
3.323
 CB
N
 C2
O
PHE C:198 C:198 0.0 0.0 S 71.4 0.1 0.0 0.0 0.0 3L8
MG
HOH
 8.652
9.633
3.486
 CB
N
N
 C2
MG
O
PHE D:198 D:198 0.0 0.0 S 81.0 4.5 0.0 0.0 0.0 3L8
MG
HOH
 8.491
9.803
3.231
 CD2
N
N
 C2
MG
O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 PHE A:204 A:198 0.0 0.0 T 74.2 6.1 0.0 0.0 0.0 SV2
SO4
MG
HOH
 8.006
9.698
9.483
3.417
 CB
C
C
N
 N2
O4
MG
O
PHE B:204 B:198 0.0 0.0 T 71.9 6.2 0.0 0.0 0.0 SV2
SO4
MG
HOH
 7.926
9.640
9.635
3.400
 CB
C
C
N
 N2
O1
MG
O
PHE C:204 C:198 0.0 0.0 S 75.9 3.4 0.0 0.0 0.0 SV2
MG
SO4
HOH
 7.942
9.351
9.798
3.306
 CB
N
C
N
 N2
MG
O1
O
PHE D:204 D:198 0.0 0.0 T 77.5 6.5 0.0 0.0 0.0 MG
SV2
SO4
HOH
 9.541
7.982
9.625
3.390
 C
CB
C
N
 MG
N2
O4
O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 PHE A:197 A:198 1.0 0.005 S 54.5 34.0 1.0 0.005 0.0 1RP
HOH
 7.230
2.539
 HB2
O
 FAI
O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 PHE A:199 A:198 0.0 0.0 T 75.1 6.3 0.0 0.0 0.0 WPG
MG
HOH
 7.291
9.474
3.347
 CB
C
N
 N2
MG
O
PHE B:199 B:198 0.0 0.0 T 74.8 5.6 0.0 0.0 0.0 WPG
MG
HOH
 7.343
9.519
3.270
 CB
C
N
 N2
MG
O
PHE C:199 C:198 0.0 0.0 T 72.4 4.4 0.0 0.0 0.0 WPG
MG
HOH
 7.327
9.431
3.404
 CB
C
N
 N2
MG
O
PHE D:199 D:198 0.0 0.0 T 70.3 7.4 0.0 0.0 0.0 WPG
MG
HOH
 7.315
9.345
3.422
 CB
C
N
 N2
MG
O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 PHE A:205 A:198 0.0 0.0 T 73.9 6.1 0.0 0.0 0.0 YPG
MG
HOH
 7.264
9.462
3.386
 CB
C
N
 N2
MG
O
PHE B:205 B:198 0.0 0.0 T 74.4 7.2 0.0 0.0 0.0 YPG
MG
HOH
 7.340
9.518
3.469
 CB
C
N
 N2
MG
O
PHE C:205 C:198 0.0 0.0 S 77.0 1.9 0.0 0.0 0.0 YPG
MG
HOH
 7.346
9.461
3.344
 CB
C
N
 N2
MG
O
PHE D:205 D:198 0.0 0.0 T 77.7 4.2 0.0 0.0 0.0 YPG
MG
HOH
 7.271
9.426
3.359
 CB
C
N
 N2
MG
O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 PHE A:199 A:198 0.0 0.0 S 69.5 12.1 0.0 0.0 0.0 4X2
HOH
 8.680
3.270
 CB
N
 C15
O
PHE B:199 B:198 0.0 0.0 S 68.4 8.4 0.0 0.0 0.0 4X2
HOH
 8.690
3.413
 CB
N
 C15
O
PHE C:199 C:198 12.0 0.057 S 64.3 27.1 12.0 0.057 0.0 4X2
HOH
 8.741
2.569
 O
N
 C15
O
PHE D:199 D:198 0.0 0.0 S 76.5 12.1 0.0 0.0 0.0 4X2
HOH
 8.729
3.297
 CB
N
 C15
O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 PHE A:199 A:198 0.0 0.0 S 62.8 15.3 0.0 0.0 0.0 4X7
HOH
 7.549
7.218
 CD2
O
 N2
O
PHE B:199 B:198 0.0 0.0 S 64.5 16.3 0.0 0.0 0.0 4X7
HOH
 7.918
3.236
 CD2
N
 N2
O
PHE C:199 C:198 0.0 0.0 S 62.4 15.8 0.0 0.0 0.0 4X7
HOH
 7.634
3.389
 CD2
N
 N2
O
PHE D:199 D:198 0.0 0.0 62.7 21.5 0.0 0.0 0.0 4X7
HOH
 7.633
3.432
 CD2
N
 N2
O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 PHE A:196 A:198 0.0 0.0 S 71.5 3.4 0.0 0.0 0.0 9YP
HOH
 7.839
3.256
 CB
N
 NAA
O
PHE B:196 B:198 0.0 0.0 T 67.4 5.7 0.0 0.0 0.0 9YP
HOH
 7.858
3.315
 CB
N
 NAA
O
PHE C:196 C:198 0.0 0.0 S 69.3 5.8 0.0 0.0 0.0 9YP
HOH
 7.881
3.468
 CB
N
 NAA
O
PHE D:196 D:198 0.0 0.0 S 70.6 5.5 0.0 0.0 0.0 9YP
HOH
 8.059
3.494
 CB
N
 NAA
O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 PHE A:195 A:198 0.0 0.0 S 47.2 80.1 0.0 0.0 0.0 PPO
HOH
 7.971
7.955
 O
CZ
 C2
O
PHE B:195 B:198 0.0 0.0 76.3 35.0 0.0 0.0 0.0 PPO
PRP
HOH
 7.677
7.418
4.446
 CB
O
N
 O6
O1B
O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 PHE A:207 A:207 9.0 0.043 S -112.1 49.4 9.0 0.043 0.0 5GP
HOH
 8.223
7.580
 CD1
CZ
 N2
O
PHE B:207 B:207 17.0 0.081 T -104.7 44.8 17.0 0.081 0.0 5GP
HOH
 7.736
6.096
 CD1
N
 N2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 PHE A:199 A:199 0.0 0.0 S 69.4 -1.8