Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133632707 . A C CCDS14641.1:NM_000194.2:c.602gAt>gCt_NP_000185.1:p.201D>A Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 ASP A:200 A:200 87.0 0.58 S -83.9 61.6 1.0 0.007 0.573 B:P00492:0.573
 HOH
 3.038
 O
 O
ASP B:200 B:200 95.0 0.633 S -79.7 55.0 4.0 0.027 0.606 A:P00492:0.607
 HOH
 2.646
 O
 O
ASP C:200 C:200 87.0 0.58 S -86.3 60.9 7.0 0.047 0.533 D:P00492:0.533
 HOH
 2.950
 O
 O
ASP D:200 D:200 88.0 0.587 S -85.7 63.6 5.0 0.033 0.554 C:P00492:0.553
 HOH
 2.912
 O
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 ASP A:200 A:200 79.0 0.527 T -94.5 -1.6 2.0 0.013 0.514 B:P00492:0.513
 HOH
 3.739
 OD1
 O
ASP B:200 B:200 80.0 0.533 T -94.5 8.2 10.0 0.067 0.466 A:P00492:0.467
 HOH
 3.072
 OD1
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 ASP A:200 A:200 75.0 0.5 T -82.1 -1.6 5.0 0.033 0.467 B:P00492:0.467
 HOH
 2.938
 OD1
 O
ASP B:200 B:200 75.0 0.5 T -82.3 -3.8 4.0 0.027 0.473 A:P00492:0.473
 HOH
 3.721
 OD1
 O
ASP C:200 C:200 71.0 0.473 T -79.4 -3.3 NA NA NA
ASP D:200 D:200 84.0 0.56 T -84.4 -0.7 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ASP A:200 A:200 76.0 0.507 T -89.7 -5.5 8.0 0.053 0.454 B:P00492:0.453
 HOH
 3.332
 O
 O
ASP B:200 B:200 78.0 0.52 T -80.4 -4.5 6.0 0.04 0.48 A:P00492:0.48
 HOH
 3.605
 CB
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ASP A:200 A:200 86.0 0.573 T -91.5 4.7 4.0 0.027 0.546 B:P00492:0.547
 HOH
 3.227
 O
 O
ASP B:200 B:200 76.0 0.507 T -85.1 0.2 6.0 0.04 0.467 A:P00492:0.467
 HOH
 3.792
 OD1
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ASP A:200 A:200 80.0 0.533 T -86.8 2.1 3.0 0.02 0.513 B:P00492:0.513
 HOH
 3.044
 O
 O
ASP B:200 B:200 76.0 0.507 T -81.5 -4.4 9.0 0.06 0.447 A:P00492:0.447
 HOH
 3.504
 OD1
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:200 A:200 93.0 0.62 S -85.6 56.4 7.0 0.047 0.573 C:P00492:0.573
 HOH
 2.855
 O
 O
ASP B:200 B:200 91.0 0.607 S -81.7 49.4 6.0 0.04 0.567 D:P00492:0.567
 HOH
 2.752
 O
 O
ASP C:200 C:200 89.0 0.593 S -86.2 51.2 10.0 0.067 0.526 A:P00492:0.527
 HOH
 2.791
 O
 O
ASP D:200 D:200 89.0 0.593 S -85.8 53.0 6.0 0.04 0.553 B:P00492:0.553
 HOH
 2.872
 O
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:200 A:200 89.0 0.593 S -84.0 54.2 5.0 0.033 0.56 C:P00492:0.56
 HOH
 2.935
 O
 O
ASP B:200 B:200 91.0 0.607 T -88.6 46.5 12.0 0.08 0.527 D:P00492:0.527
 HOH
 3.362
 OD1
 O
ASP C:200 C:200 86.0 0.573 S -81.7 52.6 2.0 0.013 0.56 A:P00492:0.56
 HOH
 2.870
 O
 O
ASP D:200 D:200 90.0 0.6 S -82.2 51.2 2.0 0.013 0.587 B:P00492:0.587
 HOH
 2.623
 O
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:200 A:200 94.0 0.627 S -85.7 53.2 8.0 0.053 0.574 C:P00492:0.573
 HOH
 2.789
 O
 O
ASP B:200 B:200 97.0 0.647 T -79.7 1.2 5.0 0.033 0.614 D:P00492:0.613
 HOH
 2.943
 HA
 O
ASP C:200 C:200 99.0 0.66 T -79.3 0.2 10.0 0.067 0.593 A:P00492:0.593
 3L5
HOH
 9.503
2.481
 N
HB2
 OAE
O
ASP D:200 D:200 91.0 0.607 S -83.5 54.8 8.0 0.053 0.554 B:P00492:0.553
 HOH
 2.733
 O
 O
ASP E:200 E:200 93.0 0.62 S -85.8 47.5 NA NA NA
ASP F:200 F:200 90.0 0.6 S -80.5 53.0 NA NA NA
ASP G:200 G:200 88.0 0.587 S -78.1 56.9 NA NA NA
ASP H:200 H:200 90.0 0.6 T -89.2 28.3 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:200 A:200 89.0 0.593 S -82.7 53.7 7.0 0.047 0.546 C:P00492:0.547
 HOH
 4.206
 O
 O
ASP B:200 B:200 90.0 0.6 T -83.7 14.3 8.0 0.053 0.547 D:P00492:0.547
ASP C:200 C:200 87.0 0.58 T -86.2 38.8 6.0 0.04 0.54 A:P00492:0.54
ASP D:200 D:200 92.0 0.613 S -83.4 58.2 8.0 0.053 0.56 B:P00492:0.56
 HOH
 4.474
 O
 O
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:200 A:200 90.0 0.6 S -88.1 57.4 5.0 0.033 0.567 C:P00492:0.567
 HOH
 2.629
 O
 O
ASP B:200 B:200 93.0 0.62 T -89.3 46.2 8.0 0.053 0.567 D:P00492:0.567
 HOH
 2.784
 O
 O
ASP C:200 C:200 92.0 0.613 T -89.0 42.5 9.0 0.06 0.553 A:P00492:0.553
 HOH
 2.897
 O
 O
ASP D:200 D:200 88.0 0.587 S -87.6 57.0 8.0 0.053 0.534 B:P00492:0.533
 HOH
 2.597
 O
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:200 A:200 89.0 0.593 S -85.8 57.7 5.0 0.033 0.56 C:P00492:0.56
 HOH
 3.381
 OD1
 O
ASP B:200 B:200 87.0 0.58 T -74.4 37.3 9.0 0.06 0.52 D:P00492:0.52
 HOH
 2.579
 O
 O
ASP C:200 C:200 91.0 0.607 T -90.7 34.3 9.0 0.06 0.547 A:P00492:0.547
 HOH
 3.399
 N
 O
ASP D:200 D:200 90.0 0.6 S -84.9 55.2 3.0 0.02 0.58 B:P00492:0.58
 HOH
 2.451
 O
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 ASP A:206 A:200 92.0 0.613 S -88.7 52.3 8.0 0.053 0.56 C:P00492:0.56
 HOH
 3.403
 OD1
 O
ASP B:206 B:200 92.0 0.613 T -89.4 49.8 7.0 0.047 0.566 D:P00492:0.567
 HOH
 3.027
 O
 O
ASP C:206 C:200 90.0 0.6 S -83.4 51.3 3.0 0.02 0.58 A:P00492:0.58
 HOH
 2.674
 O
 O
ASP D:206 D:200 88.0 0.587 S -87.7 58.2 5.0 0.033 0.554 B:P00492:0.553
 HOH
 2.713
 O
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 ASP A:199 A:200 82.0 0.547 S -87.7 8.2 82.0 0.547 0.0 HOH
 4.347
 HA
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 ASP A:201 A:200 91.0 0.607 S -87.0 52.3 9.0 0.06 0.547 C:P00492:0.547
 HOH
 2.657
 OD2
 O
ASP B:201 B:200 89.0 0.593 S -84.7 48.4 7.0 0.047 0.546 D:P00492:0.547
 HOH
 2.713
 O
 O
ASP C:201 C:200 89.0 0.593 S -83.8 52.8 4.0 0.027 0.566 A:P00492:0.567
 HOH
 2.750
 OD2
 O
ASP D:201 D:200 92.0 0.613 S -84.9 55.7 10.0 0.067 0.546 B:P00492:0.547
 HOH
 2.557
 OD2
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 ASP A:207 A:200 90.0 0.6 S -85.5 55.7 12.0 0.08 0.52 C:P00492:0.52
 HOH
 2.651
 OD2
 O
ASP B:207 B:200 90.0 0.6 T -87.4 45.9 8.0 0.053 0.547 D:P00492:0.547
 HOH
 2.708
 OD2
 O
ASP C:207 C:200 91.0 0.607 T -85.9 41.4 13.0 0.087 0.52 A:P00492:0.52
 HOH
 3.071
 O
 O
ASP D:207 D:200 91.0 0.607 S -85.5 58.9 12.0 0.08 0.527 B:P00492:0.527
 HOH
 2.797
 OD2
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 ASP A:201 A:200 93.0 0.62 S -78.3 52.3 9.0 0.06 0.56 D:P00492:0.56
 HOH
 2.359
 OD2
 O
ASP B:201 B:200 96.0 0.64 S -76.8 46.9 5.0 0.033 0.607 C:P00492:0.607
 HOH
 2.992
 O
 O
ASP C:201 C:200 127.0 0.847 S -84.6 0.2 29.0 0.193 0.654 B:P00492:0.653
 HOH
 2.355
 OD1
 O
ASP D:201 D:200 88.0 0.587 T -88.9 35.9 8.0 0.053 0.534 A:P00492:0.533
 HOH
 2.618
 O
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 ASP A:201 A:200 82.0 0.547 S -81.9 -7.7 1.0 0.007 0.54 C:P00492:0.54
 HOH
 6.902
 O
 O
ASP B:201 B:200 82.0 0.547 S -78.3 -12.1 1.0 0.007 0.54 D:P00492:0.54
 HOH
 2.827
 OD2
 O
ASP C:201 C:200 84.0 0.56 T -86.4 -7.2 2.0 0.013 0.547 A:P00492:0.547
 HOH
 3.219
 OD2
 O
ASP D:201 D:200 75.0 0.5 S -82.5 -13.3 1.0 0.007 0.493 B:P00492:0.493
 HOH
 2.895
 OD2
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 ASP A:198 A:200 91.0 0.607 T -83.7 24.1 8.0 0.053 0.554 C:P00492:0.553
 HOH
 2.838
 O
 O
ASP B:198 B:200 89.0 0.593 T -85.2 45.5 7.0 0.047 0.546 D:P00492:0.547
 HOH
 2.882
 O
 O
ASP C:198 C:200 87.0 0.58 S -85.9 54.0 8.0 0.053 0.527 A:P00492:0.527
 HOH
 2.783
 O
 O
ASP D:198 D:200 89.0 0.593 T -89.8 45.9 7.0 0.047 0.546 B:P00492:0.547
 HOH
 2.864
 O
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 ASP A:197 A:200 77.0 0.513 S -88.0 40.8 1.0 0.007 0.506 B:P00492:0.507
ASP B:197 B:200 81.0 0.54 S -114.1 16.0 13.0 0.087 0.453 A:P00492:0.453
 HOH
 3.711
 OD2
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 ASP A:209 A:209 102.0 0.68 T -103.0 3.9 102.0 0.68 0.0 HOH
 8.737
 O
 O
ASP B:209 B:209 96.0 0.64 T -98.6 14.0 96.0 0.64 0.0 HOH
 3.459
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 ASP A:201 A:201 97.0 0.647 T -84.2 -1.1