Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133634061 . A C CCDS14641.1:NM_000194.2:c.611cAt>cCt_NP_000185.1:p.204H>P Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 HIS A:203 A:203 26.0 0.133 S -91.5 151.0 3.0 0.015 0.118 C:P00492:0.113
B:P00492:0.021
 IMU
HOH
 9.607
2.959
 O
CE1
 N2
O
HIS B:203 B:203 19.0 0.097 S -96.2 156.5 1.0 0.005 0.092 D:P00492:0.087
A:P00492:0.01
 IMU
HOH
 9.597
3.497
 O
CE1
 N2
O
HIS C:203 C:203 22.0 0.113 S -92.2 149.4 1.0 0.005 0.108 D:P00492:0.015
A:P00492:0.103
 IMU
HOH
 9.598
3.369
 O
ND1
 N2
O
HIS D:203 D:203 20.0 0.103 S -93.2 147.2 0.0 0.0 0.103 C:P00492:0.005
B:P00492:0.097
 IMU
HOH
 9.583
3.422
 O
ND1
 N2
O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 HIS A:203 A:203 22.0 0.113 S -90.0 152.5 2.0 0.01 0.103 B:P00492:0.103
 HOH
 3.967
 CE1
 O
HIS B:203 B:203 21.0 0.108 S -105.3 146.1 2.0 0.01 0.098 A:P00492:0.097
 HOH
 3.334
 CE1
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 HIS A:203 A:203 25.0 0.128 S -94.4 153.2 7.0 0.036 0.092 B:P00492:0.092
 HOH
 3.212
 NE2
 O
HIS B:203 B:203 26.0 0.133 S -93.1 158.1 7.0 0.036 0.097 A:P00492:0.097
 HOH
 3.157
 NE2
 O
HIS C:203 C:203 28.0 0.144 S -93.7 152.2 NA NA NA
HIS D:203 D:203 15.0 0.077 S -93.3 156.7 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 HIS A:203 A:203 20.0 0.103 S -107.2 148.0 5.0 0.026 0.077 B:P00492:0.077
 HOH
 3.633
 NE2
 O
HIS B:203 B:203 26.0 0.133 S -105.6 150.8 8.0 0.041 0.092 A:P00492:0.092
 HOH
 3.760
 NE2
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 HIS A:203 A:203 18.0 0.092 S -102.4 158.9 4.0 0.021 0.071 B:P00492:0.072
 HOH
 3.579
 NE2
 O
HIS B:203 B:203 25.0 0.128 S -97.6 151.1 9.0 0.046 0.082 A:P00492:0.082
 HOH
 3.626
 NE2
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 HIS A:203 A:203 21.0 0.108 S -101.2 155.4 6.0 0.031 0.077 B:P00492:0.077
 HOH
 3.652
 NE2
 O
HIS B:203 B:203 26.0 0.133 S -103.3 156.9 8.0 0.041 0.092 A:P00492:0.092
 25H
HOH
 9.956
3.657
 O
CE1
 N2
O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 HIS A:203 A:203 23.0 0.118 S -90.9 151.8 4.0 0.021 0.097 C:P00492:0.026
B:P00492:0.082
 3L3
HOH
 9.813
3.319
 O
NE2
 N2
O
HIS B:203 B:203 15.0 0.077 S -86.4 151.8 2.0 0.01 0.067 A:P00492:0.067
 3L3
HOH
 9.983
3.399
 O
NE2
 N2
O
HIS C:203 C:203 15.0 0.077 S -87.1 154.9 2.0 0.01 0.067 D:P00492:0.067
A:P00492:0.005
 3L3
HOH
 9.800
3.393
 O
NE2
 N2
O
HIS D:203 D:203 14.0 0.072 S -87.0 153.8 1.0 0.005 0.067 C:P00492:0.067
 3L3
HOH
 9.758
3.563
 O
NE2
 N2
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 HIS A:203 A:203 25.0 0.128 S -85.2 151.5 4.0 0.021 0.107 C:P00492:0.021
B:P00492:0.092
 3L4
HOH
 9.906
3.282
 O
CE1
 N2
O
HIS B:203 B:203 17.0 0.087 S -91.0 149.6 2.0 0.01 0.077 A:P00492:0.072
 HOH
 3.458
 CD2
 O
HIS C:203 C:203 23.0 0.118 S -86.5 146.4 4.0 0.021 0.097 D:P00492:0.087
A:P00492:0.015
 HOH
 3.537
 CE1
 O
HIS D:203 D:203 22.0 0.113 S -94.4 151.4 5.0 0.026 0.087 C:P00492:0.077
B:P00492:0.01
 HOH
 3.863
 NE2
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 HIS A:203 A:203 14.0 0.072 S -89.2 156.6 3.0 0.015 0.057 B:P00492:0.056
 3L5
HOH
 9.848
2.845
 O
HD2
 H23
O
HIS B:203 B:203 13.0 0.067 S -87.5 159.1 1.0 0.005 0.062 A:P00492:0.062
 3L5
HOH
 9.304
2.701
 O
HE1
 H24
O
HIS C:203 C:203 13.0 0.067 S -93.1 158.6 2.0 0.01 0.057 D:P00492:0.056
 3L5
HOH
 9.466
2.661
 O
HE1
 H23
O
HIS D:203 D:203 13.0 0.067 S -86.0 151.8 1.0 0.005 0.062 C:P00492:0.062
 3L5
HOH
 9.801
2.949
 O
HE1
 H24
O
HIS E:203 E:203 27.0 0.138 S -86.0 154.3 NA NA NA
HIS F:203 F:203 14.0 0.072 S -81.1 155.0 NA NA NA
HIS G:203 G:203 14.0 0.072 S -85.9 148.0 NA NA NA
HIS H:203 H:203 24.0 0.123 S -87.9 146.7 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 HIS A:203 A:203 26.0 0.133 S -81.7 150.6 3.0 0.015 0.118 C:P00492:0.026
B:P00492:0.103
 HOH
 4.692
 N
 O
HIS B:203 B:203 21.0 0.108 S -105.6 156.3 2.0 0.01 0.098 D:P00492:0.01
A:P00492:0.092
HIS C:203 C:203 22.0 0.113 S -91.8 152.8 4.0 0.021 0.092 D:P00492:0.082
A:P00492:0.015
 HOH
 6.653
 CE1
 O
HIS D:203 D:203 26.0 0.133 S -85.1 154.8 3.0 0.015 0.118 C:P00492:0.113
B:P00492:0.015
 HOH
 4.955
 N
 O
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 HIS A:203 A:203 24.0 0.123 S -92.3 153.9 4.0 0.021 0.102 C:P00492:0.021
B:P00492:0.092
 HOH
 3.752
 NE2
 O
HIS B:203 B:203 15.0 0.077 S -90.5 154.6 1.0 0.005 0.072 A:P00492:0.072
 HOH
 3.343
 CE1
 O
HIS C:203 C:203 16.0 0.082 S -91.1 157.8 2.0 0.01 0.072 D:P00492:0.072
 HOH
 3.465
 CD2
 O
HIS D:203 D:203 23.0 0.118 S -92.3 156.8 4.0 0.021 0.097 B:P00492:0.026
C:P00492:0.077
 HOH
 3.848
 NE2
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 HIS A:203 A:203 18.0 0.092 S -85.8 151.4 1.0 0.005 0.087 C:P00492:0.01
B:P00492:0.087
 HOH
 3.880
 NE2
 O
HIS B:203 B:203 19.0 0.097 S -81.9 152.6 1.0 0.005 0.092 D:P00492:0.005
A:P00492:0.092
 HOH
 3.777
 NE2
 O
HIS C:203 C:203 16.0 0.082 S -93.1 155.1 1.0 0.005 0.077 D:P00492:0.077
A:P00492:0.005
 HOH
 3.129
 NE2
 O
HIS D:203 D:203 18.0 0.092 S -89.6 153.0 2.0 0.01 0.082 C:P00492:0.082
B:P00492:0.01
 HOH
 5.301
 N
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 HIS A:209 A:203 24.0 0.123 S -91.1 153.7 4.0 0.021 0.102 C:P00492:0.015
B:P00492:0.092
 HOH
 3.360
 ND1
 O
HIS B:209 B:203 16.0 0.082 S -92.7 150.3 2.0 0.01 0.072 D:P00492:0.005
A:P00492:0.072
 HOH
 3.355
 NE2
 O
HIS C:209 C:203 24.0 0.123 S -95.0 152.0 5.0 0.026 0.097 D:P00492:0.082
A:P00492:0.021
 HOH
 3.832
 CE1
 O
HIS D:209 D:203 23.0 0.118 S -96.2 154.6 4.0 0.021 0.097 B:P00492:0.015
C:P00492:0.082
 HOH
 3.366
 ND1
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 HIS A:202 A:203 24.0 0.123 S -92.1 138.0 24.0 0.123 0.0 HOH
 6.432
 O
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 HIS A:204 A:203 13.0 0.067 S -87.3 157.5 1.0 0.005 0.062 B:P00492:0.062
 WPG
HOH
 9.884
3.349
 O
CD2
 N2
O
HIS B:204 B:203 14.0 0.072 S -82.3 154.2 1.0 0.005 0.067 A:P00492:0.067
 WPG
HOH
 9.896
3.237
 O
CE1
 N2
O
HIS C:204 C:203 13.0 0.067 S -87.1 156.9 2.0 0.01 0.057 D:P00492:0.056
 WPG
HOH
 9.897
3.360
 O
CE1
 N2
O
HIS D:204 D:203 14.0 0.072 S -86.8 157.8 2.0 0.01 0.062 B:P00492:0.005
C:P00492:0.056
 WPG
HOH
 9.927
3.255
 O
CD2
 N2
O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 HIS A:210 A:203 14.0 0.072 S -85.6 156.3 1.0 0.005 0.067 B:P00492:0.067
 YPG
HOH
 9.909
3.322
 O
CD2
 N2
O
HIS B:210 B:203 14.0 0.072 S -83.8 160.0 2.0 0.01 0.062 A:P00492:0.062
 YPG
HOH
 9.899
3.429
 O
CD2
 N2
O
HIS C:210 C:203 15.0 0.077 S -86.8 154.4 2.0 0.01 0.067 D:P00492:0.067
 YPG
HOH
 9.919
3.481
 O
CD2
 N2
O
HIS D:210 D:203 14.0 0.072 S -89.0 155.3 2.0 0.01 0.062 C:P00492:0.062
 YPG
HOH
 9.905
3.199
 O
CD2
 N2
O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 HIS A:204 A:203 14.0 0.072 S -78.8 162.9 3.0 0.015 0.057 C:P00492:0.056
 HOH
 3.482
 CD2
 O
HIS B:204 B:203 27.0 0.138 S -82.9 149.2 4.0 0.021 0.117 D:P00492:0.097
C:P00492:0.031
 HOH
 3.396
 NE2
 O
HIS C:204 C:203 25.0 0.128 S -117.9 154.7 14.0 0.072 0.056 A:P00492:0.056
B:P00492:0.005
 HOH
 3.478
 CE1
 O
HIS D:204 D:203 15.0 0.077 S -82.8 153.6 1.0 0.005 0.072 B:P00492:0.072
 HOH
 3.376
 CE1
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 HIS A:204 A:203 13.0 0.067 S -92.0 147.1 0.0 0.0 0.067 D:P00492:0.067
 HOH
 3.477
 NE2
 O
HIS B:204 B:203 22.0 0.113 S -94.0 148.8 7.0 0.036 0.077 C:P00492:0.077
 HOH
 3.533
 CE1
 O
HIS C:204 C:203 13.0 0.067 S -92.7 143.7 0.0 0.0 0.067 B:P00492:0.067
 HOH
 3.554
 CE1
 O
HIS D:204 D:203 26.0 0.133 S -96.5 144.1 11.0 0.056 0.077 A:P00492:0.077
 HOH
 3.523
 CE1
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 HIS A:201 A:203 24.0 0.123 S -91.8 157.5 4.0 0.021 0.102 C:P00492:0.026
B:P00492:0.077
 HOH
 3.422
 CE1
 O
HIS B:201 B:203 17.0 0.087 S -86.0 161.4 1.0 0.005 0.082 A:P00492:0.082
 HOH
 3.282
 CE1
 O
HIS C:201 C:203 28.0 0.144 S -89.7 140.3 4.0 0.021 0.123 D:P00492:0.082
A:P00492:0.041
 HOH
 3.146
 NE2
 O
HIS D:201 D:203 17.0 0.087 S -96.1 166.3 2.0 0.01 0.077 C:P00492:0.077
 HOH
 3.485
 CE1
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 HIS A:200 A:203 19.0 0.097 S -89.6 116.7 19.0 0.097 0.0
HIS B:200 B:203 28.0 0.144 S -97.3 104.6 28.0 0.144 0.0 HOH
 5.876
 CE1
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 HIS A:212 A:212 20.0 0.103 S -103.7 148.0 6.0 0.031 0.072 B:P20035+P00492:0.072
 HOH
 6.207
 CE1
 O
HIS B:212 B:212 20.0 0.103 S -95.1 146.9 5.0 0.026 0.077 A:P20035+P00492:0.077
 5GP
HOH
 9.825
4.056
 O
CD2
 N2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 HIS A:204 A:204 11.0 0.056 S -76.0 149.8