Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 135741294 | . | A | C | CCDS14659.1:NM_000074.2:c.506tAt>tCt_NP_000065.1:p.169Y>S | Homo sapiens CD40 ligand (CD40LG), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1aly | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
1997-09-17 | TYR | A:54 | A:169 | 0.0 | 0.0 | E | -126.6 | 138.7 | 0.0 | 0.0 | 0.0 |
HOH |
1.808 |
HH |
H1 |
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| 1i9r | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2002-03-20 | TYR | A:54 | A:169 | 0.0 | 0.0 | E | -148.4 | 150.6 | 0.0 | 0.0 | 0.0 | ||||||
| TYR | B:54 | B:169 | 0.0 | 0.0 | E | -150.4 | 148.4 | 0.0 | 0.0 | 0.0 | |||||||||||||
| TYR | C:54 | C:169 | 0.0 | 0.0 | E | -144.5 | 151.6 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6w9g | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2020-12-23 | TYR | A:54 | A:169 | 0.0 | 0.0 | E | -130.8 | 143.3 | 0.0 | 0.0 | 0.0 |
TRS HOH |
7.916 2.857 |
C OH |
O3 O |
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| TYR | B:54 | B:169 | 0.0 | 0.0 | E | -131.2 | 141.9 | 0.0 | 0.0 | 0.0 |
TRS HOH |
8.181 2.839 |
CA OH |
O2 O |
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| TYR | C:54 | C:169 | 0.0 | 0.0 | E | -126.9 | 144.5 | 0.0 | 0.0 | 0.0 |
TRS HOH |
8.279 2.833 |
CA OH |
C2 O |
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| 7sgm | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2022-02-02 | TYR | A:54 | A:169 | 0.0 | 0.0 | E | -133.6 | 145.3 | 0.0 | 0.0 | 0.0 |
TRS HOH |
8.215 2.865 |
CA OH |
C2 O |
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| TYR | B:54 | B:169 | 0.0 | 0.0 | E | -134.8 | 140.2 | 0.0 | 0.0 | 0.0 |
TRS HOH |
8.314 2.790 |
CA OH |
C1 O |
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| TYR | C:54 | C:169 | 0.0 | 0.0 | E | -132.3 | 142.5 | 0.0 | 0.0 | 0.0 |
TRS HOH |
8.212 2.827 |
C OH |
C3 O |
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| 3qd6 | 1 | P29965 | 100.0 | 1e-106 |
X-RAY |
2011-02-02 | TYR | A:57 | A:169 | 0.0 | 0.0 | E | -113.8 | 163.2 | 0.0 | 0.0 | 0.0 | ||||||
| TYR | B:57 | B:169 | 0.0 | 0.0 | E | -105.8 | 167.0 | 0.0 | 0.0 | 0.0 | |||||||||||||
| TYR | C:57 | C:169 | 0.0 | 0.0 | E | -109.4 | 166.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| TYR | D:57 | D:169 | 0.0 | 0.0 | E | -106.8 | 159.8 | NA | NA | NA | |||||||||||||
| TYR | E:57 | E:169 | 0.0 | 0.0 | E | -104.3 | 168.6 | NA | NA | NA | |||||||||||||
| TYR | F:57 | F:169 | 0.0 | 0.0 | E | -112.1 | 160.3 | NA | NA | NA | |||||||||||||
| 6brb | 1 | P29965 | 100.0 | 5e-103 |
X-RAY |
2018-12-05 | TYR | A:50 | A:169 | 0.0 | 0.0 | E | -128.4 | 146.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.377 |
N |
O |
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| 3lkj | 1 | P29965 | 100.0 | 6e-102 |
X-RAY |
2011-02-02 | TYR | A:49 | A:169 | 0.0 | 0.0 | E | -117.5 | 142.1 | 0.0 | 0.0 | 0.0 |
LKJ HOH |
6.908 4.999 |
O N |
C50 O |
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| TYR | B:49 | B:169 | 0.0 | 0.0 | E | -124.1 | 131.0 | 0.0 | 0.0 | 0.0 |
LKJ HOH |
7.962 7.779 |
C CD1 |
C34 O |
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| TYR | C:49 | C:169 | 0.0 | 0.0 | E | -119.9 | 138.0 | 0.0 | 0.0 | 0.0 |
LKJ HOH |
6.455 2.668 |
C OH |
C40 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p29965-f1 | 1 | P29965 | 100.0 | 0.0 | TYR | A:169 | A:169 | 0.0 | 0.0 | E | -129.8 | 132.1 | |