Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 24906160 | . | G | A | CCDS14214.1:NM_016937.3:c.4067cGa>cAa_NP_058633.2:p.1356R>Q | Homo sapiens DNA polymerase alpha 1, catalytic subunit (POLA1), transcript variant 2, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5exr | 3 | P09884 | 99.91 | 0.0 |
X-RAY |
2016-03-23 | ARG | C:1022 | C:1356 | 128.0 | 0.569 | E | -94.0 | 104.3 | 105.0 | 0.467 | 0.102 |
D:Q14181:0.102 |
ZN |
7.807 |
N |
ZN |
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| ARG | G:1022 | G:1356 | 115.0 | 0.511 | E | -96.6 | 105.0 | NA | NA | NA | |||||||||||||
| 7opl | 1 | P09884 | 100.0 | 0.0 |
EM |
2021-11-10 | ARG | A:1064 | A:1356 | 119.0 | 0.529 | E | -105.9 | 109.8 | 107.0 | 0.476 | 0.053 |
B:Q14181:0.053 |
ZN |
7.570 |
N |
ZN |
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| 4y97 | 2 | P09884 | 100.0 | 5e-125 |
X-RAY |
2015-04-15 | ARG | B:92 | B:1356 | 106.0 | 0.471 | E | -121.0 | 122.0 | 85.0 | 0.378 | 0.093 |
A:Q14181:0.093 |
ZN HOH |
7.399 3.171 |
N NH1 |
ZN O |
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| ARG | D:92 | D:1356 | 115.0 | 0.511 | E | -120.1 | 122.4 | NA | NA | NA | |||||||||||||
| ARG | F:92 | F:1356 | 110.0 | 0.489 | E | -119.0 | 121.4 | NA | NA | NA | |||||||||||||
| ARG | H:92 | H:1356 | 106.0 | 0.471 | E | -120.0 | 120.3 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p09884-f1 | 1 | P09884 | 100.0 | 0.0 | ARG | A:1356 | A:1356 | 103.0 | 0.458 | E | -114.0 | 101.3 | |