Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 66863196 | . | A | C | CCDS14387.1:NM_000044.3:c.1715tAt>tCt_NP_000035.2:p.572Y>S | Homo sapiens androgen receptor (AR), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1r4i | 3 | P15207 | 95.24 | 9e-56 |
X-RAY |
2004-06-29 | TYR | C:22 | A:554 | 84.0 | 0.365 | T | 47.2 | -1.4 | 84.0 | 0.365 | 0.0 |
DC DC DA DG DA DT |
9.894 5.244 2.940 3.110 7.863 9.986 |
N N N OH OH OH |
O3' O3' OP1 OP2 OP2 O4 |
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| TYR | D:22 | B:554 | 76.0 | 0.33 | S | 46.6 | 11.3 | 76.0 | 0.33 | 0.0 |
DA DC DT DG DT |
9.768 5.588 3.529 2.983 6.320 |
OH N N OH OH |
N6 O3' OP1 OP2 C7 |
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| 4oor | 1 | ? | 83.95 | 2e-44 |
X-RAY |
2014-10-29 | TYR | A:19 | A:19 | 70.0 | 0.304 | T | 52.1 | 30.0 | 70.0 | 0.304 | 0.0 |
DT DC DA DG DA HOH |
9.416 5.033 3.233 2.454 8.141 3.983 |
N N N OH OH CE1 |
O3' O3' OP2 OP2 OP2 O |
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| TYR | B:19 | B:19 | 74.0 | 0.322 | T | 52.1 | 30.1 | 74.0 | 0.322 | 0.0 |
DC DC DA DG DA |
9.659 5.195 3.331 2.467 8.034 |
N N N OH OH |
O3' O3' OP1 OP2 OP2 |
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| TYR | C:19 | E:19 | 68.0 | 0.296 | T | 52.5 | 30.0 | NA | NA | NA | |||||||||||||
| TYR | D:19 | F:19 | 74.0 | 0.322 | T | 51.6 | 30.0 | NA | NA | NA | |||||||||||||
| 4ov7 | 1 | ? | 83.95 | 2e-44 |
X-RAY |
2014-10-29 | TYR | A:19 | A:19 | 70.0 | 0.304 | T | 52.1 | 30.0 | 70.0 | 0.304 | 0.0 |
DT DC DA DG DA HOH |
9.416 5.033 3.233 2.454 8.141 3.983 |
N N N OH OH CE1 |
O3' O3' OP2 OP2 OP2 O |
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| TYR | B:19 | B:19 | 74.0 | 0.322 | T | 52.1 | 30.1 | 74.0 | 0.322 | 0.0 |
DC DC DA DG DA |
9.659 5.195 3.331 2.467 8.034 |
N N N OH OH |
O3' O3' OP1 OP2 OP2 |
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| TYR | C:19 | E:19 | 68.0 | 0.296 | T | 52.5 | 30.0 | NA | NA | NA | |||||||||||||
| TYR | D:19 | F:19 | 74.0 | 0.322 | T | 51.6 | 30.0 | NA | NA | NA | |||||||||||||
| 5cc0 | 1 | ? | 83.95 | 3e-44 |
X-RAY |
2015-12-23 | TYR | A:22 | A:433 | 78.0 | 0.339 | T | 57.4 | 33.2 | 78.0 | 0.339 | 0.0 |
DC DC DG DG DG |
9.396 5.133 3.421 2.639 7.825 |
N N N OH OH |
O3' O3' OP1 OP2 OP2 |
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| TYR | D:22 | B:433 | 65.0 | 0.283 | T | 59.0 | 23.9 | 65.0 | 0.283 | 0.0 |
DC DC DG DG DA |
9.655 5.038 2.917 2.589 7.630 |
N N N OH OH |
O3' O3' OP1 OP2 OP2 |
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| 4ond | 1 | ? | 80.25 | 6e-42 |
X-RAY |
2014-10-29 | TYR | A:19 | A:19 | 66.0 | 0.287 | T | 56.7 | 29.4 | 66.0 | 0.287 | 0.0 |
DA DC DT DC DA DG DG DT HOH |
9.938 9.994 9.445 5.062 3.166 3.428 7.644 9.405 3.246 |
OH OH N N N OH OH OH OH |
N6 N4 O3' O3' OP2 OP2 N7 O4 O |
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| TYR | B:19 | B:19 | 65.0 | 0.283 | T | 56.8 | 28.4 | 65.0 | 0.283 | 0.0 |
DC DC DA DG DG DT DA DC HOH |
9.491 5.082 3.059 3.330 7.320 9.189 9.866 9.794 3.375 |
N N N OH OH OH OH OH N |
O3' O3' OP1 OP2 N7 O4 N6 N4 O |
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| TYR | C:19 | E:19 | 64.0 | 0.278 | T | 57.9 | 27.2 | NA | NA | NA | |||||||||||||
| TYR | D:19 | F:19 | 74.0 | 0.322 | T | 56.5 | 31.5 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p10275-f1 | 1 | P10275 | 100.0 | 0.0 | TYR | A:572 | A:572 | 30.0 | 0.13 | T | 60.0 | 13.8 | |