Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 66863224 | . | G | A | CCDS14387.1:NM_000044.3:c.1743aaG>aaA_NP_000035.2:p.581K>K | Homo sapiens androgen receptor (AR), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1r4i | 3 | P15207 | 95.24 | 9e-56 |
X-RAY |
2004-06-29 | LYS | C:31 | A:563 | 73.0 | 0.365 | H | -46.9 | -66.9 | 73.0 | 0.365 | 0.0 |
DC DA DG DA DA DT DG DT DT DC DT DG ZN |
6.094 4.004 3.360 4.410 7.170 9.314 7.793 6.122 4.525 5.818 7.340 9.741 6.015 |
CD NZ NZ NZ NZ C N CE NZ NZ NZ NZ N |
C2' N7 N7 N6 N6 C2' OP2 C7 O4 N4 O4 N1 ZN |
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| LYS | D:31 | B:563 | 75.0 | 0.375 | H | -62.9 | -70.4 | 75.0 | 0.375 | 0.0 |
DA DG DA DA DC DA DG DC DT DG DT DT ZN |
9.312 7.266 7.207 5.695 6.258 7.603 9.398 6.062 3.978 3.390 4.410 7.684 5.827 |
C N NZ NZ NZ NZ NZ CE CE NZ NZ NZ N |
C2' OP2 N6 N6 N4 N1 N2 C2' C7 N7 O4 O4 ZN |
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| 4oor | 1 | ? | 83.95 | 2e-44 |
X-RAY |
2014-10-29 | LYS | A:28 | A:28 | 66.0 | 0.33 | H | -62.0 | -63.7 | 66.0 | 0.33 | 0.0 |
DT DG DT DT DC DT DG DC DA DG DA DA ZN HOH |
9.496 7.430 6.174 5.996 7.145 8.836 9.612 5.740 4.457 3.153 5.311 7.130 5.996 6.340 |
N N NZ NZ CE CE NZ CD CE NZ NZ NZ N N |
C2' OP2 O4 O4 N4 O4 N2 C2' N7 N7 N6 N6 ZN O |
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| LYS | B:28 | B:28 | 62.0 | 0.31 | H | -62.0 | -62.5 | 62.0 | 0.31 | 0.0 |
DC DC DA DG DA DA DT DG DT DT DC DT DG ZN |
9.664 5.727 4.386 2.971 4.799 7.326 9.537 7.430 6.191 5.605 6.844 9.090 9.405 6.014 |
CD CD CD NZ NZ NZ N N NZ NZ NZ NZ NZ N |
C2' C2' OP2 N7 N6 N6 C2' OP2 O4 O4 N4 N3 N2 ZN |
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| LYS | C:28 | E:28 | 67.0 | 0.335 | H | -62.0 | -63.6 | NA | NA | NA | |||||||||||||
| LYS | D:28 | F:28 | 64.0 | 0.32 | H | -61.6 | -63.3 | NA | NA | NA | |||||||||||||
| 4ov7 | 1 | ? | 83.95 | 2e-44 |
X-RAY |
2014-10-29 | LYS | A:28 | A:28 | 66.0 | 0.33 | H | -62.0 | -63.7 | 66.0 | 0.33 | 0.0 |
DT DG DT DT DC DT DG DC DA DG DA DA ZN HOH |
9.496 7.430 6.174 5.996 7.145 8.836 9.612 5.740 4.457 3.153 5.311 7.130 5.996 6.340 |
N N NZ NZ CE CE NZ CD CE NZ NZ NZ N N |
C2' OP2 O4 O4 N4 O4 N2 C2' N7 N7 N6 N6 ZN O |
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| LYS | B:28 | B:28 | 62.0 | 0.31 | H | -62.0 | -62.5 | 62.0 | 0.31 | 0.0 |
DC DC DA DG DA DA DT DG DT DT DC DT DG ZN |
9.664 5.727 4.386 2.971 4.799 7.326 9.537 7.430 6.191 5.605 6.844 9.090 9.405 6.014 |
CD CD CD NZ NZ NZ N N NZ NZ NZ NZ NZ N |
C2' C2' OP2 N7 N6 N6 C2' OP2 O4 O4 N4 N3 N2 ZN |
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| LYS | C:28 | E:28 | 67.0 | 0.335 | H | -62.0 | -63.6 | NA | NA | NA | |||||||||||||
| LYS | D:28 | F:28 | 64.0 | 0.32 | H | -61.6 | -63.3 | NA | NA | NA | |||||||||||||
| 5cc0 | 1 | ? | 83.95 | 3e-44 |
X-RAY |
2015-12-23 | LYS | A:31 | A:442 | 84.0 | 0.42 | H | -57.0 | -54.5 | 84.0 | 0.42 | 0.0 |
DC DG DG DG DA DT DC DT DC DC DC DG ZN |
6.407 4.057 2.687 4.856 7.381 9.412 7.583 5.711 4.666 5.863 7.191 8.632 5.905 |
CD NZ NZ NZ NZ N N CE NZ NZ NZ NZ N |
C2' N7 N7 O6 N6 C2' OP2 C7 N4 N4 N4 N1 ZN |
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| LYS | D:31 | B:442 | 74.0 | 0.37 | H | -59.0 | -49.3 | 74.0 | 0.37 | 0.0 |
DC DG DC DC DT DC DC DG DC DC DG DG DA DG ZN |
9.365 7.497 8.098 7.329 7.608 8.546 9.913 8.972 9.533 4.994 3.399 4.917 6.908 8.532 6.026 |
C N CD CE CE CE NZ NZ NZ NZ NZ NZ CE CE N |
O5' OP2 C5 N4 O4 N4 N4 N2 C2' C2' OP2 N7 N6 O6 ZN |
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| 4ond | 1 | ? | 80.25 | 6e-42 |
X-RAY |
2014-10-29 | LYS | A:28 | A:28 | 54.0 | 0.27 | H | -59.7 | -56.7 | 54.0 | 0.27 | 0.0 |
DT DG DA DC DC DT DC DA DG DG DT ZN HOH |
9.021 7.107 5.322 4.783 6.108 8.638 6.215 4.768 3.765 4.113 6.438 5.941 2.822 |
C N NZ CE CE CE CD CD NZ NZ NZ N NZ |
C2' OP2 N6 N4 N4 O4 C2' N7 N7 O6 O4 ZN O |
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| LYS | B:28 | B:28 | 62.0 | 0.31 | H | -56.9 | -60.2 | 62.0 | 0.31 | 0.0 |
DC DC DA DG DG DT DT DG DA DC DC DT DG ZN HOH |
9.703 5.547 3.994 2.912 4.683 7.171 9.101 7.076 6.578 5.620 6.360 8.775 9.167 5.936 4.417 |
CE CE CE NZ NZ NZ C N NZ NZ NZ NZ NZ N CD |
C2' C2' N7 N7 O6 O4 C2' OP2 N6 N4 N4 O4 N2 ZN O |
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| LYS | C:28 | E:28 | 66.0 | 0.33 | H | -58.3 | -60.9 | NA | NA | NA | |||||||||||||
| LYS | D:28 | F:28 | 55.0 | 0.275 | H | -59.6 | -56.3 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p10275-f1 | 1 | P10275 | 100.0 | 0.0 | LYS | A:581 | A:581 | 75.0 | 0.375 | H | -51.9 | -52.7 | |