Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 66905909 | . | G | A | CCDS14387.1:NM_000044.3:c.1826aGg>aAg_NP_000035.2:p.609R>K | Homo sapiens androgen receptor (AR), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1r4i | 3 | P15207 | 95.24 | 9e-56 |
X-RAY |
2004-06-29 | ARG | C:59 | A:591 | 41.0 | 0.182 | T | -62.2 | -23.1 | 41.0 | 0.182 | 0.0 |
DA DT DG DT ZN ZN |
7.428 5.310 3.354 4.710 4.615 8.829 |
O O CD NH2 NH1 O |
O3' OP1 OP1 OP2 ZN ZN |
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| ARG | D:59 | B:591 | 50.0 | 0.222 | G | -30.2 | -31.6 | 50.0 | 0.222 | 0.0 |
DA DA DG DA ZN ZN |
8.566 5.176 2.695 5.262 4.343 8.242 |
O NE NE NH2 NH1 O |
O3' O3' OP1 OP1 ZN ZN |
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| 4oor | 1 | ? | 83.95 | 2e-44 |
X-RAY |
2014-10-29 | ARG | A:56 | A:56 | 23.0 | 0.102 | T | -65.5 | -25.1 | 23.0 | 0.102 | 0.0 |
DG DT DG DT ZN ZN HOH |
7.399 5.131 2.704 4.446 8.981 4.009 3.819 |
O NE NE NH2 O NH1 NH2 |
O3' O3' OP1 OP1 ZN ZN O |
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| ARG | B:56 | B:56 | 24.0 | 0.107 | T | -64.2 | -24.7 | 24.0 | 0.107 | 0.0 |
DC DT DG DT ZN ZN HOH |
7.702 5.181 2.717 4.325 4.127 8.824 6.230 |
O NE NE NH2 NH1 O C |
O3' O3' OP1 OP1 ZN ZN O |
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| ARG | C:56 | E:56 | 22.0 | 0.098 | T | -66.0 | -26.5 | NA | NA | NA | |||||||||||||
| ARG | D:56 | F:56 | 30.0 | 0.133 | T | -66.9 | -26.4 | NA | NA | NA | |||||||||||||
| 4ov7 | 1 | ? | 83.95 | 2e-44 |
X-RAY |
2014-10-29 | ARG | A:56 | A:56 | 23.0 | 0.102 | T | -65.5 | -25.1 | 23.0 | 0.102 | 0.0 |
DG DT DG DT ZN ZN HOH |
7.399 5.131 2.704 4.446 8.981 4.009 3.819 |
O NE NE NH2 O NH1 NH2 |
O3' O3' OP1 OP1 ZN ZN O |
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| ARG | B:56 | B:56 | 24.0 | 0.107 | T | -64.2 | -24.7 | 24.0 | 0.107 | 0.0 |
DC DT DG DT ZN ZN HOH |
7.702 5.181 2.717 4.325 4.127 8.824 6.230 |
O NE NE NH2 NH1 O C |
O3' O3' OP1 OP1 ZN ZN O |
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| ARG | C:56 | E:56 | 22.0 | 0.098 | T | -66.0 | -26.5 | NA | NA | NA | |||||||||||||
| ARG | D:56 | F:56 | 30.0 | 0.133 | T | -66.9 | -26.4 | NA | NA | NA | |||||||||||||
| 5cc0 | 1 | ? | 83.95 | 3e-44 |
X-RAY |
2015-12-23 | ARG | A:59 | A:470 | 45.0 | 0.2 | T | -48.0 | -44.9 | 45.0 | 0.2 | 0.0 |
DC DT DC DT ZN ZN HOH |
7.659 4.408 2.273 3.972 4.971 8.775 7.655 |
O NH1 NH1 NH2 CD O O |
O3' O3' OP1 OP1 ZN ZN O |
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| ARG | D:59 | B:470 | 25.0 | 0.111 | T | -42.7 | -49.7 | 25.0 | 0.111 | 0.0 |
DC DG DC ZN ZN |
5.189 3.124 4.714 4.723 8.964 |
NH1 NH1 NH1 NE O |
O3' OP1 OP2 ZN ZN |
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| 4ond | 1 | ? | 80.25 | 6e-42 |
X-RAY |
2014-10-29 | ARG | A:56 | A:56 | 28.0 | 0.124 | T | -74.2 | -21.7 | 28.0 | 0.124 | 0.0 |
DG DT DG DA ZN ZN HOH |
7.449 5.168 2.828 4.182 8.910 3.974 2.850 |
O O NE NH2 O NH1 O |
O3' OP1 OP1 OP1 ZN ZN O |
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| ARG | B:56 | B:56 | 37.0 | 0.164 | T | -67.3 | -26.4 | 37.0 | 0.164 | 0.0 |
DC DT DG DA ZN ZN HOH |
7.709 5.226 2.791 4.091 3.888 8.792 2.958 |
O NE NE NH2 NH1 O O |
O3' O3' OP1 OP1 ZN ZN O |
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| ARG | C:56 | E:56 | 51.0 | 0.227 | T | -71.0 | -26.9 | NA | NA | NA | |||||||||||||
| ARG | D:56 | F:56 | 35.0 | 0.156 | T | -61.6 | -23.4 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p10275-f1 | 1 | P10275 | 100.0 | 0.0 | ARG | A:609 | A:609 | 35.0 | 0.156 | G | -60.1 | -1.0 | |